ID A0A099FW16_9RHOB Unreviewed; 494 AA.
AC A0A099FW16; A0A099FR27; A0A099G2M2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Nucleobase:cation symporter-2, NCS2 family {ECO:0000313|EMBL:SDW45744.1};
DE SubName: Full=Permease {ECO:0000313|EMBL:KGJ17069.1};
GN ORFNames=IX56_17615 {ECO:0000313|EMBL:KGJ17069.1},
GN SAMN05444276_1011027 {ECO:0000313|EMBL:SDW45744.1};
OS Paracoccus sanguinis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=1545044 {ECO:0000313|EMBL:KGJ17069.1, ECO:0000313|Proteomes:UP000029858};
RN [1] {ECO:0000313|EMBL:KGJ17069.1, ECO:0000313|Proteomes:UP000029858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5503 {ECO:0000313|EMBL:KGJ17069.1,
RC ECO:0000313|Proteomes:UP000029858};
RA McGinnis J.M., Wolfgang W.J.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KGJ17069.1, ECO:0000313|Proteomes:UP000029858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5503 {ECO:0000313|EMBL:KGJ17069.1,
RC ECO:0000313|Proteomes:UP000029858};
RA Mingle L.A., Cole J.A., Lapierre P., Musser K.A.;
RT "Paracoccus sanguinis sp. nov., isolated from clinical specimens of New
RT York State patients.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SDW45744.1, ECO:0000313|Proteomes:UP000182944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 29303 {ECO:0000313|EMBL:SDW45744.1,
RC ECO:0000313|Proteomes:UP000182944};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; JRKQ01000192; KGJ17069.1; -; Genomic_DNA.
DR EMBL; FNNA01000001; SDW45744.1; -; Genomic_DNA.
DR RefSeq; WP_036705713.1; NZ_JRKT01000137.1.
DR STRING; 1545044.SAMN05444276_1011027; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000029858; Unassembled WGS sequence.
DR Proteomes; UP000182944; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 2.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029858};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 23..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 494 AA; 51364 MW; 0D7AD36B6235A594 CRC64;
MTDLTHSRGT LDPVEAVPPA PRLFALGLQH VLVMYAGAIA VPLIVGRALK LSPEDVAFLI
SADLFVCGIA SIIQSMGAGA WLGVRLPVMM GVTFAAVGPM VAIANETPGE IGARALFGAV
IGAGIVAVLL APLVSRMLRF FPPVVTGTVI LTIGISLMPI GINWIFGLQQ GPTAPKLVDP
AMQAWLDAQV AAGGVPLGTK IAASVPNPLY AAPRNFLIAG VVLATILLIA RFGRGFLSNI
AVLIGIVVGG LLAASMGMMH FEKVAAAAWF APIRPFHFGM PTFDPVMILT MTLVMIVVMI
ESTGMFLALG DMVGHRISQP RLAAGLRADG VGTILGGVFN TFPYTSFSQN VGLVGVTGVR
SRFVCVAGGA IMIVLGLIPK MGALVEALPT VVLGGAGLVM FGMVAATGVR ILSRVDFTAN
RHNLFIVAIA IGMGMIPMIA GDFDQWLPRG TRVLTHSGIL LAAVSAVLLN WFFNGAKPVD
EDELRRAGAA ADSH
//
