ID A0A099J523_9MICO Unreviewed; 336 AA.
AC A0A099J523;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Inositol 2-dehydrogenase {ECO:0000313|EMBL:KGJ72592.1, ECO:0000313|EMBL:MBB5642897.1};
DE EC=1.1.1.18 {ECO:0000313|EMBL:MBB5642897.1};
DE EC=1.1.1.369 {ECO:0000313|EMBL:MBB5642897.1};
GN ORFNames=BJ997_003445 {ECO:0000313|EMBL:MBB5642897.1}, GY21_14255
GN {ECO:0000313|EMBL:KGJ72592.1};
OS Cryobacterium roopkundense.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Cryobacterium.
OX NCBI_TaxID=1001240 {ECO:0000313|EMBL:KGJ72592.1, ECO:0000313|Proteomes:UP000029864};
RN [1] {ECO:0000313|EMBL:KGJ72592.1, ECO:0000313|Proteomes:UP000029864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RuG17 {ECO:0000313|EMBL:KGJ72592.1,
RC ECO:0000313|Proteomes:UP000029864};
RA Sisinthy S.;
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBB5642897.1, ECO:0000313|Proteomes:UP000561726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21065 {ECO:0000313|EMBL:MBB5642897.1,
RC ECO:0000313|Proteomes:UP000561726};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGJ72592.1}.
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DR EMBL; JPXF01000064; KGJ72592.1; -; Genomic_DNA.
DR EMBL; JACHBQ010000001; MBB5642897.1; -; Genomic_DNA.
DR RefSeq; WP_035837511.1; NZ_JPXF01000064.1.
DR AlphaFoldDB; A0A099J523; -.
DR STRING; 1001240.GY21_14255; -.
DR eggNOG; COG0673; Bacteria.
DR OrthoDB; 256869at2; -.
DR Proteomes; UP000029864; Unassembled WGS sequence.
DR Proteomes; UP000561726; Unassembled WGS sequence.
DR GO; GO:0050112; F:inositol 2-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR030827; Myo_inos_IolG.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR04380; myo_inos_iolG; 1.
DR PANTHER; PTHR42840:SF3; BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED; 1.
DR PANTHER; PTHR42840; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:MBB5642897.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029864}.
FT DOMAIN 5..122
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 137..332
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 336 AA; 35757 MW; 828E5BA9BA9BA2A4 CRC64;
MTTPLRFGLF GTGRIGQVHA ASIASSPRAS LQWVCDPFVD GANATAAKYG GRATAEPADL
FAAEDIDALI IASSTPTHVE LIDQALDAGI PVLCEKPIDL DITRVDALRA KADAATVPVV
LGFNRRFDPH FAELQRRVAS GEIGALEQLA IVSRDPAEPP AAYVAVSGGI FRDMTIHDFD
MARFFLPNIV SVTARGANQF SPAIAAAGDF DAVVVTLEAE GGELVTITNS RHSAFGYDQR
FEAFGSEGML QVGNIGPSVI RSYSTSLVEA QGAYHSFFLE RYADAYRFEL EAFIDTVAGE
PSRSPGFEDG RAALILADAA ELSARTGRTV DVDLRA
//
