ID A0A099TV31_9HELI Unreviewed; 312 AA.
AC A0A099TV31;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Cobalamin syntheis protein, P47K family ATP/GTP binding protein {ECO:0000313|EMBL:STQ86287.1};
DE SubName: Full=GTP-binding protein {ECO:0000313|EMBL:TLE01663.1};
GN Name=yjiA {ECO:0000313|EMBL:STQ86287.1};
GN ORFNames=LS73_000555 {ECO:0000313|EMBL:TLE01663.1}, NCTC12714_01092
GN {ECO:0000313|EMBL:STQ86287.1};
OS Helicobacter muridarum.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=216 {ECO:0000313|EMBL:STQ86287.1, ECO:0000313|Proteomes:UP000255139};
RN [1] {ECO:0000313|EMBL:TLE01663.1, ECO:0000313|Proteomes:UP000029922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST1 {ECO:0000313|EMBL:TLE01663.1,
RC ECO:0000313|Proteomes:UP000029922};
RX PubMed=25428971;
RA Sheh A., Shen Z., Fox J.G.;
RT "Draft genome sequences of eight enterohepatic helicobacter species
RT isolated from both laboratory and wild rodents.";
RL Genome Announc. 2:e01218-e01214(2014).
RN [2] {ECO:0000313|EMBL:STQ86287.1, ECO:0000313|Proteomes:UP000255139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12714 {ECO:0000313|EMBL:STQ86287.1,
RC ECO:0000313|Proteomes:UP000255139};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; UGJE01000002; STQ86287.1; -; Genomic_DNA.
DR EMBL; JRPD02000001; TLE01663.1; -; Genomic_DNA.
DR RefSeq; WP_034559224.1; NZ_UGJE01000002.1.
DR AlphaFoldDB; A0A099TV31; -.
DR STRING; 216.LS73_08845; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000029922; Unassembled WGS sequence.
DR Proteomes; UP000255139; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000255139}.
FT DOMAIN 214..304
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 312 AA; 35301 MW; 8F332B5265EAC057 CRC64;
MAKIAVHLIT GFLGSGKTSL IKEYLQNNQS QDTALIINEI GEISLDERVL QHYSSERILK
LSSGCVCCNK RLDLIESLKN ILNEYELRGQ KPKRIIIEST GLANPAPILW TLMNDIFLSN
HFFVKSVVTC IDSINALSHL ENEEAIAQII ASDLIIICKS DIKKPSSELI QKLKSINLSL
EIKDKAELDF QNIFDINHRF LTNEIPTNKH EQSFDTISLS FDNPLEWNAF GVWLSMLLHK
WGKKILRVKG VLDINENFLI AINGVGHIIH SPTHIPKDRQ GSSLVFITRG FESKQILDSL
NGFKRLLEIN MS
//
