ID A0A099YZG1_TINGU Unreviewed; 2447 AA.
AC A0A099YZG1;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Teneurin-2 {ECO:0000313|EMBL:KGL74842.1};
DE Flags: Fragment;
GN ORFNames=N309_11369 {ECO:0000313|EMBL:KGL74842.1};
OS Tinamus guttatus (White-throated tinamou).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Tinamiformes; Tinamidae; Tinamus.
OX NCBI_TaxID=94827 {ECO:0000313|EMBL:KGL74842.1, ECO:0000313|Proteomes:UP000053641};
RN [1] {ECO:0000313|EMBL:KGL74842.1, ECO:0000313|Proteomes:UP000053641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N309 {ECO:0000313|EMBL:KGL74842.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the tenascin family. Teneurin subfamily.
CC {ECO:0000256|ARBA:ARBA00009385}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL887318; KGL74842.1; -; Genomic_DNA.
DR STRING; 94827.A0A099YZG1; -.
DR Proteomes; UP000053641; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 7.
DR Gene3D; 2.180.10.10; RHS repeat-associated core; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR008969; CarboxyPept-like_regulatory.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR009471; Ten_N.
DR InterPro; IPR028916; Tox-GHH_dom.
DR InterPro; IPR006530; YD.
DR NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR NCBIfam; TIGR01643; YD_repeat_2x; 1.
DR PANTHER; PTHR11219; TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR11219:SF8; TENEURIN-2; 1.
DR Pfam; PF06484; Ten_N; 1.
DR Pfam; PF15636; Tox-GHH; 1.
DR SMART; SM00181; EGF; 8.
DR SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR SUPFAM; SSF101898; NHL repeat; 2.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS51361; TENEURIN_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053641};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..60
FT /note="Teneurin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51361"
FT DOMAIN 350..382
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 384..417
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 479..514
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 372..381
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 407..416
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 483..493
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 504..513
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL74842.1"
FT NON_TER 2447
FT /evidence="ECO:0000313|EMBL:KGL74842.1"
SQ SEQUENCE 2447 AA; 271778 MW; 5E28A2D5065F7DC2 CRC64;
RHFLFKTSSG TTPLFSSSSP GYPLTSGTVY TPPPRLLPRN TFSRNAFKLK KPSKYCSWKC
AALSAIAAAV LLAILLAYFI AMHLLGLNWQ LQPADGHTFN NGVRGGAAEA PASPVGGRGP
WVTRNSSIDS GEAEVGRRVT QEVPPGVFWR SQIHINQPQF LKFNISLGKD ALFGVYIRRG
LPPSHAQYDF MERLDGKEKW SVVESPRERR SIQTLVQNEA VFVQYLDVGL WHLAFYNDGK
DKEVVSFSTV ILDSVQDCPR NCHGNGECVS GVCHCFPGFH GADCAKAACP VLCSGNGQYT
KGTCLCYSGW KGPECDVPVS QCIDPSCGGH GSCIEGNCVC SVGYKGENCE EVDCLDPTCS
NHGVCVNGEC LCSPGWGGIN CELPRAQCPD QCSGHGTYLS DTGLCSCDPN WMGPDCSVEV
CSVDCGTHGV CIGGACRCEE GWTGVACDQR VCHPRCTEHG TCKDGKCECR EGWNGEHCTI
DGCPDLCNGN GRCTLGQNSW QCVCQTGWRG PGCNVAMETS CADNKDNEGD GLVDCLDPDC
CLQSTCQNSL LCRGSRDPLD IIQQSHSGSP AVKSFYDRIK LLVGKDSTHI IPGENPFNSS
LVSLIRGQVV TTDGTPLVGV NVSFVKYPKY GYTITRQDGT FDLVANGGAS LTLHFERAPF
MTQERTVWLP WNSFYAMDTL VMKTEENSIP SCDLSGFVRP DPVIISSPLS TFFSDTPGRN
PIVPETQVLH EEIEIPGSTI KLNYLSSRTA GYKSLLKITM TQSLVPLNLI KVHLMVAVEG
HLFQKSFQAS PNLAYTFIWD KTDAYGQKVY GLSDAVVSVG FEYETCPSLI LWEKRTALLQ
GFELDPSNLG GWSLDKHHVL NVKNGILHKG NGENQFLTQQ PAVITSIMGN GRRRSISCPS
CNGLAEGNKL LAPVALAVGT DGSLFVGDFN YIRRIFPSRN VTSILELRNK EFKHSNNPAH
KYYLAVDPVS GSLYVSDTNS RRIYKVKSLT GTKDLASNSE VVAGTGEQCL PFDEARCGDG
GKAVDATLMS PRGIAVDKYG LMYFVDATMI RKVDQNGIIS TLLGSNDLTA VRPLSCDSSM
DVTQVRLEWP TDLAVNPMDN SLYVLENNVI LRITENHQVS IIAGRPMHCQ VPGIDYSLSK
LAIHSALESA SAIAISHTGV LYISETDEKK INRLRQVTTN GEICLLAGAA SDCDCKNDVN
CNCYSGDDGY ATDAILNSPS SLAVAPDGTI YIADLGNTRI RAVSKNRPVL NSFNQYEAAS
PGEQELYVFN ADGIHQYTLS LVTGEYLYNF TYSSDNDVTE VMDNNGNSLK VRRDTSGMPR
HLLMPDNQIV TLAIGTNGAL KLVSTQTLEL GLMTYNGNSG LLATKSDETG WTTFYDYDHE
GRLTNVTRPT GVVTSLHREM EKSITIDIEN SNRDDDVTVI TNLSSVEASY TVVQDQVRNS
YQLCNNGTLR VMYANGMSIS FHSEPHVLAG TVTPTIGRCN ISLPMENGLN SIEWRLRKEQ
IKGKVTVFGR KLRVHGRNLL SIDYDRNIRT EKIYDDHRKF TLRIIYDQLG RPFLWLPSSG
LAAVNVSYFF NGRLAGLQRG AMSERTDIDK QGRIISRMFA DGKVWSYTYL EKSMVLLLQS
QRQYIFEYDS SDRLHAVTMP SVARHSVSTH TSVGYIRNIY NPPESNASVI FDYSDDGRIL
KTSFLGTGRQ VFYKYGKLSK LSEIVYDSTA VTFGYDETTG VLKMVNLQSG GFSCTIRYRK
IGPLVDKQIY RFSEEGMVNA RFDYTYHDNS FRIASIKPII SETPLPVDLY RYDEISGKVE
HFGKFGVIYY DINQIITTAV MTLSKHFDTH GRIKEVQYEM FRSLMYWMTV QYDSMGRVTK
RELKLGPYAN TTKYTYDYDG DGQLQSVAVN DRPTWRYSYD LNGNLHLLSP GNSVRLMPLR
YDLRDRITRL GDIPYKIDED GFLCQRGSDV FEYNSKGLLT RAYNKGNGWN IQYRYDGLGR
RASCKTNLGH HLQYFYADLH NPTRVTHVYN HSNSEITSLY YDLQGHLFAM ESSSGEEYYV
ASDNTGTPLA VFSINGLMIK QLQYTAYGEI YYDSNPDFQM VIGFHGGLYD PLTKLVHFTQ
RDYDVLAGRW TSPDYTMWKN VGREPAPFNL YMFKSNNPLS NELDLKNYVT DVKSWLVMFG
FQLSNIIPGF PRAKMYFVSP PYELSESQAC ENGQLITGVQ QTTERHNQAF MALEGQVISK
RLHASIREKA GHWFATTTPI IGKGIMFAVK EGRVTTGVSS IAAEDSRKVA SVLNGAHYLE
KMHYSIEGKD THYFVKIGSA DSDLVTLAMT SGRKVLDSGV NVTVSQPTLL VNGRTRRFTN
IEFQHATLLL NIRYGLTPDT LDEEKARVLD QARQRALGAA WAKEQQKARD GREGSRVWTD
GEKQQLLNTG RVQGYEGYYV LPVEQYPELA DSSSNIQFLR QNEMGKR
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