ID A0A099ZC21_TINGU Unreviewed; 1051 AA.
AC A0A099ZC21;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 03-MAY-2023, entry version 29.
DE SubName: Full=Small G protein signaling modulator 1 {ECO:0000313|EMBL:KGL79326.1};
DE Flags: Fragment;
GN ORFNames=N309_09780 {ECO:0000313|EMBL:KGL79326.1};
OS Tinamus guttatus (White-throated tinamou).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Tinamiformes; Tinamidae; Tinamus.
OX NCBI_TaxID=94827 {ECO:0000313|EMBL:KGL79326.1, ECO:0000313|Proteomes:UP000053641};
RN [1] {ECO:0000313|EMBL:KGL79326.1, ECO:0000313|Proteomes:UP000053641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N309 {ECO:0000313|EMBL:KGL79326.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RUTBC family.
CC {ECO:0000256|ARBA:ARBA00034124}.
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DR EMBL; KL892026; KGL79326.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A099ZC21; -.
DR STRING; 94827.A0A099ZC21; -.
DR Proteomes; UP000053641; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProt.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd15784; PH_RUTBC; 1.
DR CDD; cd17703; RUN_SGSM1; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR Gene3D; 2.30.29.230; -; 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047344; RUN_SGSM1.
DR InterPro; IPR037745; SGSM1/2.
DR InterPro; IPR021935; SGSM1/2_RBD.
DR PANTHER; PTHR22957:SF187; SMALL G PROTEIN SIGNALING MODULATOR 1; 1.
DR PANTHER; PTHR22957; TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF12068; PH_RBD; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50826; RUN; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053641}.
FT DOMAIN 16..170
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 525..984
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 369..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..733
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL79326.1"
FT NON_TER 1051
FT /evidence="ECO:0000313|EMBL:KGL79326.1"
SQ SEQUENCE 1051 AA; 118349 MW; 6AE6D4C9354782C4 CRC64;
QVKQIMEEAV TRKFVHEDSS HIISFCAAVE ACVLHGLKRR AAGFLRSNKI AALFMKVGKS
FPLAEELCKK VQDLEQLIEN ARNQVQGVPE SVRKVPKLPN LSPQAIKHLW IRTALFEKVL
DKIVHYLVEN SSKYYEKEAL LMDPVDGPIL ASLLVGPCAL EYTKMKTADH FWTDPSADEL
VQRHRIHSSH CRQDSPTKRP ALCIQKRHSS GSMDDRPSLS ARDYVESLHQ NSRATLLYGK
NNVLVQPRDD MEAIPGYLSL HQTADIMALK WTPNQLMNGS VGDLDYERSV YWDYAMTIRL
EEIVYLHCHQ QVDSGGTVVL VSQDGIQRPP LRFPKGGHLL QFLSCLENGL LPHGQLDPPL
WSQRGKGKVF PKLRKRSPQG SSESASDKED DEATDYVFRI IYPGTQSEFV PQELMDAQGA
GRPALLGTRT PHISCVPVGR APLKLLCDNM KYQILSRAFY GWLAYCRHLS TVRTHLSALV
NHNIVSPDVP CSASSGLTVD IWQRYLQDST SYEDRELLRL IYYGGIQHEI RRAVWPFLLG
HYQFGMTEAE RKEADAQTRT CYEHTMAEWL GCEAIVRQRE KESHAAALAK CSSGASLDSH
IQRMMHRDST ISNESSQSCS SGRQNHARLQ SDSSSSTQVF ESVDEVEQTD ADAQLEDGKQ
GKIPNGTVPN GTYSPDSGHP SSQNFSITSG FSERSFSNED SALETTKSSA SSQGKGGGSE
APAPQSSDPA LQGQDSLEGE FPPAGAMDFV RAGESSVAAL QDRDAVALTV VESWADSEAE
KQSLVESEDN LSEEPEMESL YPQLDSLAVA DLANNEASPV SSSGVTYSPE LLDMYTVNLH
RIEKDVQRCD RNYWYFTPAN LEKLRNIMCS YIWQHIEIGY VQGMCDLLAP LLVILDDEAL
AFSCFTELMK RMNQNFPHGG AMDTHFANMR SLIQILDSEL FELMHQNGDY THFYFCYRWF
LLDFKRELVY DDVFAVWETI WAAAHVSSAH YVLFIALALV EMYRDIILEN NMDFTDIIKF
FNEMAERHNT KQILKLARDL VYKVQTLIEN K
//
