ID   A0A0A0AB45_CHAVO        Unreviewed;       715 AA.
AC   A0A0A0AB45;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|EMBL:KGL90185.1};
DE   Flags: Fragment;
GN   ORFNames=N301_00131 {ECO:0000313|EMBL:KGL90185.1};
OS   Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX   NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL90185.1, ECO:0000313|Proteomes:UP000053858};
RN   [1] {ECO:0000313|EMBL:KGL90185.1, ECO:0000313|Proteomes:UP000053858}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL90185.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004401};
CC       Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane
CC       protein {ECO:0000256|ARBA:ARBA00004606}.
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC       {ECO:0000256|ARBA:ARBA00005634}.
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DR   EMBL; KL871085; KGL90185.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A0AB45; -.
DR   STRING; 50402.A0A0A0AB45; -.
DR   Proteomes; UP000053858; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd08022; M28_PSMA_like; 1.
DR   CDD; cd02121; PA_GCPII_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR039373; Peptidase_M28B.
DR   InterPro; IPR007365; TFR-like_dimer_dom.
DR   InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR   PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR   PANTHER; PTHR10404:SF38; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE 2; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   Pfam; PF04253; TFR_dimer; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053858};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022968}.
FT   DOMAIN          137..223
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          322..525
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   DOMAIN          592..712
FT                   /note="Transferrin receptor-like dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF04253"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KGL90185.1"
FT   NON_TER         715
FT                   /evidence="ECO:0000313|EMBL:KGL90185.1"
SQ   SEQUENCE   715 AA;  80579 MW;  F0CF656912AC16F2 CRC64;
     VSGWFTKPTE RTPNSSDGYQ NVRHKLVAEM KAENIKHFLR SFTKLPHLAG TEQNLLLAKQ
     IQGQWKEFGL DSAELVHYDV LLSYPNEKQP NYISVIDDQG NEIFNTSLFE PAPPGYENVT
     DIQPPYNAFS AQGVPEADLV YVNYGRTEDF FKLEREMGIN CTGKIVIARY GKIFRGNKVK
     NAILAGAQGI ILYSDPADYC APGVYAYPNG WNLPGRGAQR GNVLNLNGAG DPLTPGYPAK
     EYTFRYKVNE GVGIPKIPVH PIGYHDAEVL LRGMGGSAAP DSSWKGSLNV SYNIGPGFAD
     NSSTRKVRMH VHTNNKITRI YNVIGILRGA VEPDRYIILG GHRDSWVFGG IDPTTGTAVL
     QEVVRSFGKM KMEGWRPKRT IIFASWDAEE FGLLGSTEWA EENARVLQER AVAYINTDSS
     IEGNYTLRVD CTPLLYKLVY NLTKEILSPD EGYENKSLYD SWLDKDPATE NNSYPRINKL
     GSGSDFEAYF QRLGIASGRV RYTKNRKTDK FSNYPVYHTV YETFELVEKF YDPTFKKQLT
     VAQLRGKLVY ELADSQVIPF DCRDYGEALK GYSNRIYKLA KKHEEQLKTY KVSFDPLFSA
     VVNFSKAAAE FHRRLEQVDK KDPVAVRIMN DQLMFIERAF IDPLGLPGRK FYRHVIFAPS
     SHNKYAGESF PGIYDAMFDI ESEGDQRGAW EEVKRQISIA AFTVQAAAGT LKEVA
//