ID A0A0A0AU78_CHAVO Unreviewed; 246 AA.
AC A0A0A0AU78;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Ankyrin repeat and SOCS box protein 8 {ECO:0000256|ARBA:ARBA00017640};
DE Flags: Fragment;
GN ORFNames=N301_05368 {ECO:0000313|EMBL:KGL98139.1};
OS Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL98139.1, ECO:0000313|Proteomes:UP000053858};
RN [1] {ECO:0000313|EMBL:KGL98139.1, ECO:0000313|Proteomes:UP000053858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL98139.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be a substrate-recognition component of a SCF-like ECS
CC (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex
CC which mediates the ubiquitination and subsequent proteasomal
CC degradation of target proteins. {ECO:0000256|ARBA:ARBA00003062}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; KL873300; KGL98139.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A0AU78; -.
DR STRING; 50402.A0A0A0AU78; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000053858; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03727; SOCS_ASB8; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037332; ASB8_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24134:SF30; ANKYRIN REPEAT AND SOCS BOX PROTEIN 8; 1.
DR PANTHER; PTHR24134; ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 4.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000053858}.
FT REPEAT 10..42
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 43..74
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 75..107
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 108..140
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 193..246
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL98139.1"
FT NON_TER 246
FT /evidence="ECO:0000313|EMBL:KGL98139.1"
SQ SEQUENCE 246 AA; 27203 MW; 83E76CBFFE65AFC3 CRC64;
QGADVNCMHG TLKPLHCACM VADADCVELL LQKGAEVNAL DGYNRTALHY AAEKDETCVE
ILLEYGANPN ALDGNKDTPL HWAAFKNNAE CVRSLLENGA LVNARDYNND TPLSWAAMKG
NLESVSILLD FGAEVRVVNL KGQTPISRLV ALLVRGLGTE REDSCFDLLH RAIGHFELRK
NGRMPWEVTR DQQLCEKLTR LCSAPGTLQT LSRYAVRRSL GVRFLPEAVK QLPLPTCLKE
YVLLLS
//
