ID A0A0A0KQG2_CUCSA Unreviewed; 672 AA.
AC A0A0A0KQG2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Galectin domain-containing protein {ECO:0000259|PROSITE:PS51304};
GN ORFNames=Csa_5G604080 {ECO:0000313|EMBL:KGN51863.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN51863.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN51863.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004323}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661}.
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DR EMBL; CM002926; KGN51863.1; -; Genomic_DNA.
DR RefSeq; XP_004135209.1; XM_004135161.2.
DR AlphaFoldDB; A0A0A0KQG2; -.
DR STRING; 3659.A0A0A0KQG2; -.
DR EnsemblPlants; KGN51863; KGN51863; Csa_5G604080.
DR GeneID; 101206587; -.
DR Gramene; KGN51863; KGN51863; Csa_5G604080.
DR KEGG; csv:101206587; -.
DR eggNOG; KOG2287; Eukaryota.
DR OMA; SEFTAHK; -.
DR OrthoDB; 1207620at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000029981; Chromosome 5.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0008378; F:galactosyltransferase activity; IBA:GO_Central.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR CDD; cd00070; GLECT; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001079; Galectin_CRD.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11214:SF286; HYDROXYPROLINE O-GALACTOSYLTRANSFERASE GALT4; 1.
DR Pfam; PF00337; Gal-bind_lectin; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
DR SMART; SM00908; Gal-bind_lectin; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51304; GALECTIN; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 183..393
FT /note="Galectin"
FT /evidence="ECO:0000259|PROSITE:PS51304"
FT REGION 70..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 672 AA; 77162 MW; 4A7142F08E51CEC1 CRC64;
MKRGKFDVMV SINRIRLLQI LMGLVFLYLL FMSFEIPLVY RTGYGSVSGD GTFGFTSDAL
PRPFLLESEE EMTDKGAPRR PSDDPFRISH GSPHRTPERR MREFRKVSGL VFDESTFDRN
ATKGEFSELQ KAAKHAWVVG KKLWEELESG KIELKPKAKM ENQSESCPHS ITLSGSEFQA
QGRIMELPCG LTLWSHITVV GTPHWAHSEE DPKISILKEG DDSVLVSQFM MELQGLKTVD
GEDPPRILHF NPRLKGDWSG KPVIEQNTCY RMQWGTALRC EGWKSRADEE TVDGQVKCEK
WIRDDDSRSE ESKVIWWLNR LIGRTKKVMI DWPYPFVEGR LFVLTVSAGL EGYHINVDGR
HVTSFPYRTG FVLEDATGLS VNGDIDVHSL FAASLPTAHP SFAPQKHMEM LTQWKAPPIP
KSNVELFIGI LSAGNHFAER MAVRKSWMQH RLIRSSLAVA RFFVAMHGRK EVNTELKKEA
EYFGDIVIVP YMDNYDLVVL KTIAICEYGA RTVAAKYIMK CDDDTFVRVD AVLSEAHKVQ
AGRSLYVGNM NYHHKPLRHG KWAVTYEEWP EEDYPAYANG PGYILSSDIA EYIVSEFEKH
KLRLFKMEDV SMGMWVEQFN SSKPVKFLHS LRFCQFGCIE DYLTAHYQSP RQMMCLWDKL
MQQKKPQCCN MR
//
