ID A0A0A0LRI2_CUCSA Unreviewed; 767 AA.
AC A0A0A0LRI2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=Csa_1G050370 {ECO:0000313|EMBL:KGN64398.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN64398.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN64398.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM002922; KGN64398.1; -; Genomic_DNA.
DR RefSeq; XP_011652025.1; XM_011653723.1.
DR RefSeq; XP_011652027.1; XM_011653725.1.
DR AlphaFoldDB; A0A0A0LRI2; -.
DR STRING; 3659.A0A0A0LRI2; -.
DR EnsemblPlants; KGN64398; KGN64398; Csa_1G050370.
DR GeneID; 101215008; -.
DR Gramene; KGN64398; KGN64398; Csa_1G050370.
DR KEGG; csv:101215008; -.
DR eggNOG; ENOG502QRS8; Eukaryota.
DR OMA; FRFDHNF; -.
DR OrthoDB; 3686501at2759; -.
DR Proteomes; UP000029981; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF61; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00365; LRR_SD22; 4.
DR SMART; SM00369; LRR_TYP; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..767
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001966242"
FT TRANSMEM 396..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 486..748
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 767 AA; 84961 MW; 1B3C16242985CD88 CRC64;
MGKCDLLLLL CFAWTFLFAE AYQLQASQAQ VLLQLRKHLE YPKQLESWTD HRVDFCTLSF
LPLVNVTCQD SVVTELRIAG DTKDKVDEFI GFAIPNQTLS EGFSLDSFIT TLTRLNSLRV
LSLVSLGIWG PLPDKIHRLS SLEYLDLSSN YLFGSIPPKI STLVKLQTLK LDDNFFNDTV
PNWFDSLSSL TVLSLKNNKI KDSFPSSIVS ISTLTELVMS GNEISGELPD LSPLHGLTVL
DLSWNKLDSS LPPLPKSLIT ASLGKNSFSG EIPQQYGELS QLQQLDISFN ALAGIPPASI
FSLPNISHLN LSSNKLFGSL STHLRCGNML QFVDISNNML TGALPSCLGI ESDNRTLKVD
GNCLSVSIGK QHSKSYCDID HIQQHQHQEQ SKAKNAGAVM GLLLGIFLSV LLLSIVVVLF
RRCWPRGMSE QHLLQKSVQD SSAAGFSSEL LTSARFVSQA AKIGIQGLPL CRTFSLEEIR
EATSNFHDST IIGDGSYGKL YRGRLENGTQ VAIRSLVVSK KFSIRNLKLR LDMLGKLRHP
NLVCLLGHCI DGEGQDYHDI KVFLIFEYVS NGSFRTHLSE KVLNWSERLA ILISVAKAVH
FLHTGVIPGF FDNQLKINNI LIDEHNVAKL SDYGLSIVSE EPTKSVAKAE GPQAWQLMNL
KDDVYSFGFI LLEALVAPSV SARKGPSILK EMMSLSSQDG RRRLIDPTIL ATCTQESLST
IISLMNKCIS PEMSRPSMED VLWNLQYANQ VQDARDGDQR YSSASQQ
//
