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Database: UniProt
Entry: A0A0A0M742_9LACT
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ID   A0A0A0M742_9LACT        Unreviewed;       355 AA.
AC   A0A0A0M742;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-SEP-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Q757_02885 {ECO:0000313|EMBL:KGO32128.1};
OS   Oenococcus alcoholitolerans.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Leuconostocaceae;
OC   Oenococcus.
OX   NCBI_TaxID=931074 {ECO:0000313|EMBL:KGO32128.1, ECO:0000313|Proteomes:UP000030023};
RN   [1] {ECO:0000313|EMBL:KGO32128.1, ECO:0000313|Proteomes:UP000030023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UFRJ-M7.2.18 {ECO:0000313|EMBL:KGO32128.1,
RC   ECO:0000313|Proteomes:UP000030023};
RX   PubMed=25315101; DOI=10.1007/s10482-014-0296-z;
RA   Badotti F., Moreira A.P., Tonon L.A., de Lucena B.T., Gomes Fde C.,
RA   Kruger R., Thompson C.C., de Morais M.A.Jr., Rosa C.A., Thompson F.L.;
RT   "Oenococcus alcoholitolerans sp. nov., a lactic acid bacteria isolated
RT   from cachaca and ethanol fermentation processes.";
RL   Antonie Van Leeuwenhoek 106:1259-1267(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGO32128.1}.
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DR   EMBL; AXCV01000089; KGO32128.1; -; Genomic_DNA.
DR   EnsemblBacteria; KGO32128; KGO32128; Q757_02885.
DR   Proteomes; UP000030023; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030023};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030023}.
FT   DOMAIN       52    182       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      261    330       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND      60     67       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   355 AA;  39914 MW;  C91B73CC899DB779 CRC64;
     MVRKTDDLDQ SSFVATDYEL NSAFTFENWV VGDANELATS AAIAVSEQPG KQYNPLLIYG
     SSGLGKTHLM EAIGNKVQEL EPNAIIRYIT TDDFMNDWVD AISKKKTAEF TSNYENVDIL
     LVDDIQMLQG KTVFKKIFNI FNKITKSQKQ IVMTSDVLPK DIPGLNTRLV SRFMQGVAYD
     IQKPDYPTRL AILKNKAEET GMNIDIQTLS LIAEEVDSNV RELEGAFNTL TLMARSGKKI
     NVANAEKILE HLNITKQKVI TIEDVQRVVA EEYDVSLADL IGKKRNSDIV MPRQVAMYLI
     RHLTDISLPK IGQAFGGRDH TTVMHGTEKI ADLIEKDLTV KQRIETISAK IKERQ
//
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