ID A0A0A0MUG2_PAPAN Unreviewed; 688 AA.
AC A0A0A0MUG2;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Hook microtubule tethering protein 2 {ECO:0000313|Ensembl:ENSPANP00000001419.3};
GN Name=HOOK2 {ECO:0000313|Ensembl:ENSPANP00000001419.3};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000001419.3, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000001419.3, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000001419.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the hook family.
CC {ECO:0000256|ARBA:ARBA00006946}.
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DR AlphaFoldDB; A0A0A0MUG2; -.
DR STRING; 9555.ENSPANP00000001419; -.
DR Ensembl; ENSPANT00000011591.3; ENSPANP00000001419.3; ENSPANG00000014672.3.
DR eggNOG; ENOG502QTJ1; Eukaryota.
DR GeneTree; ENSGT00940000160152; -.
DR HOGENOM; CLU_011214_2_0_1; -.
DR Proteomes; UP000028761; Chromosome 20.
DR Bgee; ENSPANG00000014672; Expressed in cornea and 57 other cell types or tissues.
DR ExpressionAtlas; A0A0A0MUG2; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR CDD; cd22227; HkD_Hook2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR008636; Hook_C.
DR InterPro; IPR043936; HOOK_N.
DR PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR PANTHER; PTHR18947:SF37; PROTEIN HOOK HOMOLOG 2; 1.
DR Pfam; PF05622; HOOK; 2.
DR Pfam; PF19047; HOOK_N; 1.
DR SUPFAM; SSF116907; Hook domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761}.
FT DOMAIN 6..122
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT COILED 180..398
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 446..473
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 509..575
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 688 AA; 79432 MW; 6E0CFACD3B4BE726 CRC64;
MSVDKAELCG SLLTWLQTFH VPSSCASPQD LSSGLAIAYV LNQIDPSWFN EAWLQGISED
PGPNWKLKVS NLKMVLRSLV EYSQDVLAHP VSEEHLPDVS LIGEFSDPAE LGKLLQLVLG
CAISCEKKQE HIQRIMTLEE SVQHVVMEAI QELMTKDSPD SLSPETYGNF DSQSRRYYFL
SEEAEEGDEL QQRCLDLERQ LMLLSEEKQS LAQENAVLRE RVGRPEGEGT PGLTAKKLLL
LQSQLEQLQE ENFRLESGRE DERLRCAELE REVAELQHRN QALTSLAQEA QALKDEMDEL
RQSSERAGQL EATLNSCQRR LGELRELRRQ VRQLEERNAG HAERTRQLED ELRRAGSLRA
QLEAQRRQXX XXXXXXRLLA ERDSLREANE ELRCAQLQPR GLTQADPSLD PTSPPMDNLA
AEILPAELRE TLLRLQLENK RLCRQEAADR ERQEELQRHL EEANRARHGL ETQHRLNQQQ
LSELWAQVED LQKALQEQGG KTEDSVLLKR KLEEHLQKLH EADLELQRKR EYIEELEPPT
DSSTARRIEE LQHNLQKKDA DLRAMEERYR RYVDKARMVM QTMEPKQRPA AGGPPELRSL
RTQLRERDVR IRHLEMDFEK SRSQREQEEK LLISAWYNMG MALQQRAGEE RAPAHAQSFL
AQQRLATNAR RGPLGRLASL NLRPTDKH
//
