ID   A0A0A1DKL5_NOCSI        Unreviewed;       722 AA.
AC   A0A0A1DKL5;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Indolepyruvate ferredoxin oxidoreductase {ECO:0000313|EMBL:GEB16901.1};
DE   SubName: Full=Indolepyruvate oxidoreductase subunit IorA {ECO:0000313|EMBL:AIY17889.1};
DE            EC=1.2.7.8 {ECO:0000313|EMBL:AIY17889.1};
GN   ORFNames=KR76_15955 {ECO:0000313|EMBL:AIY17889.1}, NSI01_52160
GN   {ECO:0000313|EMBL:GEB16901.1};
OS   Nocardioides simplex (Arthrobacter simplex).
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Pimelobacter.
OX   NCBI_TaxID=2045 {ECO:0000313|EMBL:AIY17889.1, ECO:0000313|Proteomes:UP000030300};
RN   [1] {ECO:0000313|EMBL:AIY17889.1, ECO:0000313|Proteomes:UP000030300}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM Ac-2033D {ECO:0000313|EMBL:AIY17889.1,
RC   ECO:0000313|Proteomes:UP000030300};
RX   PubMed=25573942;
RA   Shtratnikova V.Y., Schelkunov M.I., Pekov Y.A., Fokina V.V.,
RA   Logacheva M.D., Sokolov S.L., Bragin E.Y., Ashapkin V.V., Donova M.V.;
RT   "Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM
RT   Ac-2033D.";
RL   Genome Announc. 3:0-0(2015).
RN   [2] {ECO:0000313|EMBL:GEB16901.1, ECO:0000313|Proteomes:UP000318936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 12069 {ECO:0000313|EMBL:GEB16901.1,
RC   ECO:0000313|Proteomes:UP000318936};
RA   Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT   "Whole genome shotgun sequence of Pimelobacter simplex NBRC 12069.";
RL   Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP009896; AIY17889.1; -; Genomic_DNA.
DR   EMBL; BJMC01000026; GEB16901.1; -; Genomic_DNA.
DR   RefSeq; WP_038679659.1; NZ_JAAARG010000343.1.
DR   AlphaFoldDB; A0A0A1DKL5; -.
DR   STRING; 2045.KR76_15955; -.
DR   KEGG; psim:KR76_15955; -.
DR   eggNOG; COG4231; Bacteria.
DR   HOGENOM; CLU_017727_0_0_11; -.
DR   OrthoDB; 9803617at2; -.
DR   Proteomes; UP000030300; Chromosome.
DR   Proteomes; UP000318936; Unassembled WGS sequence.
DR   GO; GO:0043805; F:indolepyruvate ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   CDD; cd02008; TPP_IOR_alpha; 1.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR045025; HACL1-like.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   PANTHER; PTHR43710; 2-HYDROXYACYL-COA LYASE; 1.
DR   PANTHER; PTHR43710:SF5; INDOLEPYRUVATE FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:AIY17889.1};
KW   Pyruvate {ECO:0000313|EMBL:AIY17889.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030300}.
FT   DOMAIN          616..647
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   722 AA;  77257 MW;  2EE7765D91FA92A6 CRC64;
     MAERSFAHEV LKLRAGEGTS FSGEGILAVT KALLQSGVAY VGGYQGAPIS HLMDVLGDAH
     EILEELGVYF ENSASEATAA AMLAASVSYP LRGAITFKST VGTNVASDAL ANLSSGGVTG
     GALVIVGEDY GEGSSIMQER SHAFAMKSQM WLLDPRPNIS AIVDAVEAGF ELSEASSTPV
     MLQLRLRSCH LYGTFTAKDN KRPPMTVTDA IENPQRQLDR IVLPPASFLH EKEKIEDRWP
     AAVEFIKRRG LNEVLGADTA DIGIIVQGGV YNTLNRAMEL LGCSDAFGNT EVPVYVMNVT
     YPVVDEEILD FCAGKRAVLL VEEGQPDYIE QNLNAILRRA GSPVALHGKD LLPVAGEYTA
     AAVTRGLDAF LQKYLPDVVR SSPSLLMPED DARSPFAPRV DAAVVRPRPP GLCTGCPERP
     IFSALKLAEK ETGKQHHVSA DIGCHLFAIN EPFNLGATTM GYGLGSAGAA ALNSKDADRR
     TIAVMGDGGF WHNGLTSGVG NAVFNQNDQL LLVVDNAYSA ATGGQDVLSS QADSVLRSTK
     HPIEKAVRGV GVNWVKTVSN TYKIGALRDV FVKALTTKEA GPKVVVAQSE CQLNRQRRVK
     PQRAKAIKEG KRVVKERFGV DADTCTGDHA CIRVSGCPSL TIKANPDPMR TDPVATVLDS
     CVGCGVCGAN AHAASLCPSF YRTDLVYNPT WRDRLLSRMR GGWIGLLTSG VERRAARYEV
     SL
//