ID A0A0A1DQL0_NOCSI Unreviewed; 498 AA.
AC A0A0A1DQL0;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 2.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN Name=gabD2_2 {ECO:0000313|EMBL:GEB16813.1};
GN ORFNames=KR76_01260 {ECO:0000313|EMBL:AIY19639.2}, NSI01_51280
GN {ECO:0000313|EMBL:GEB16813.1};
OS Nocardioides simplex (Arthrobacter simplex).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Pimelobacter.
OX NCBI_TaxID=2045 {ECO:0000313|EMBL:AIY19639.2, ECO:0000313|Proteomes:UP000030300};
RN [1] {ECO:0000313|EMBL:AIY19639.2, ECO:0000313|Proteomes:UP000030300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-2033D {ECO:0000313|EMBL:AIY19639.2,
RC ECO:0000313|Proteomes:UP000030300};
RX PubMed=25573942;
RA Shtratnikova V.Y., Schelkunov M.I., Pekov Y.A., Fokina V.V.,
RA Logacheva M.D., Sokolov S.L., Bragin E.Y., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM
RT Ac-2033D.";
RL Genome Announc. 3:0-0(2015).
RN [2] {ECO:0000313|EMBL:GEB16813.1, ECO:0000313|Proteomes:UP000318936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 12069 {ECO:0000313|EMBL:GEB16813.1,
RC ECO:0000313|Proteomes:UP000318936};
RA Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT "Whole genome shotgun sequence of Pimelobacter simplex NBRC 12069.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP009896; AIY19639.2; -; Genomic_DNA.
DR EMBL; BJMC01000025; GEB16813.1; -; Genomic_DNA.
DR RefSeq; WP_052138110.1; NZ_JAAARG010000141.1.
DR AlphaFoldDB; A0A0A1DQL0; -.
DR STRING; 2045.KR76_01260; -.
DR KEGG; psim:KR76_01260; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_5_1_11; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000030300; Chromosome.
DR Proteomes; UP000318936; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07099; ALDH_DDALDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000030300}.
FT DOMAIN 2..458
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 232
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 266
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 498 AA; 52961 MW; CD832A7F64E209B3 CRC64;
MTIAVENPAT GQVIGTVPDL TADDVAAAAR RARAAQPAWQ ALGYDGRAAV LRRMQRWIVD
HTDEVVATIC AETGKAYEDA LLAEVNYGAA AFGFWAKEAP RYLADTKVRS SQPLVAGKRL
VQRYCPLGLV GVIGPWNYPL TNSFGDCIPA LAAGNAVLLK PSEVTPLTSL LLAEGLAASG
LPDGVFGVVT GRGETGAALV DEVDMVMFTG STATGRRVAA RAAERLIPAS LELGGKDPMI
VLADADLERA ATHAAYYAMF NCGQTCISIE RCYVEESVYP AFVELVTAKV KALRQGVPAG
PGSVDVGSLT FPPQVDVVDR HVSEALAAGA RALTGGARPE RAGHWYPPTV LVDVDHSMAI
MREETFGPTL PIMAVRDADE AVRLANDSEY GLCASVFGRD LARAEDVARR LEAGAVTVND
AVVNYTALEL PMGGAKPASG IGRRHGKDGI TKYCRQQSLL VSRVHLRRDV HTYPYRSGRT
RAIRSLLGLL NRGRPGRS
//
