ID A0A0A1GY59_9LACO Unreviewed; 1045 AA.
AC A0A0A1GY59;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Permease {ECO:0000313|EMBL:BAP85834.1};
GN ORFNames=LOOC260_112970 {ECO:0000313|EMBL:BAP85834.1};
OS Paucilactobacillus hokkaidonensis JCM 18461.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Paucilactobacillus.
OX NCBI_TaxID=1291742 {ECO:0000313|EMBL:BAP85834.1, ECO:0000313|Proteomes:UP000031620};
RN [1] {ECO:0000313|EMBL:BAP85834.1, ECO:0000313|Proteomes:UP000031620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LOOC260 {ECO:0000313|EMBL:BAP85834.1,
RC ECO:0000313|Proteomes:UP000031620};
RA Tanizawa Y., Tohno M., Kaminuma E., Nakamura Y., Arita M.;
RT "Complete genome sequence and analysis of Lactobacillus hokkaidonensis
RT LOOC260T.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR EMBL; AP014680; BAP85834.1; -; Genomic_DNA.
DR RefSeq; WP_041093740.1; NZ_AP014680.1.
DR AlphaFoldDB; A0A0A1GY59; -.
DR STRING; 1291742.LOOC260_112970; -.
DR KEGG; lho:LOOC260_112970; -.
DR HOGENOM; CLU_005108_0_0_9; -.
DR Proteomes; UP000031620; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR023908; xxxLxxG_rpt.
DR NCBIfam; TIGR03057; xxxLxxG_by_4; 2.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 866..884
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 891..908
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 928..947
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 967..989
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 995..1018
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..364
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 699..1022
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 1045 AA; 111953 MW; 704CF9BB70F9D84A CRC64;
MAKFLKNHVG SLIAWIVVLI LAVFMLPNIN QLTREHSTID LPKDSQSQIA DSIQKKWGYH
QGNTYQVVAV FNNGNSAMSK TDRQNVQSTI NELKKHKSEY GIKSITAPND NSETKSQLIS
KDKSTQLVQL MISKDHGTVK KINQQLTKSI KTSGVKSYIT GSDILNDDFS GAIQDGIKKT
EIISVIFIFL VLVLVFQSPI VPLISLLTVG VSFITSLSIV TNLVEKFNFP FSNFTQVFMV
IVLFGIGTDY NILLYNQFKD ELSRGISNWK AAQRARRVAG KTILYSGSSV LIGFSALALA
KFSIYQSAIG VAVGVAVLLV VLLTLNPFFM AVLGKKMFWP SKNFDGEGTS SLWHRLSSSS
VIHPIISIFA VLIILLPFYF TFNHPLNYDD TDEISNSTPA KQGFLTVQDH FSKGTAEPST
LYIRSNHRLD NEKDLKLIDE ITRKLQADPD VKTVASVTQP GGTKVKKLYV SNQLGTVNSG
LTSAQKGLGQ LSTGSQQMTT GLGQLSNGSQ QLVDGVSQLT SQLNSQLSGS NAAQIAQLES
GLPQINNGIQ QLNSALQQSG SSIDTSSLTS ELTNVGNQAQ VIGTNLTQAG NTLQGLQGQS
SSSSDSANQI IQAANQNGAS LQPGQQAVLS AVITSALNKQ SQSLEGSLSS VAANIQAAGN
ADKSLAGSMT SVSNSAGSLN SMMSQVATLK TEVNQLATAS NTALPGAATA LTQLTSGLNQ
VQSALGSSQS GLIQINTGIN QLADQSPQLT SGIDKVNSGL GSGGSYLKAL KKSAAADSYY
VPKNILHSKS YKPAIKAYLS EDKKSAKITV VLGTNPSDAT ATKKVRTLSN MAKKNLKGTD
LKNATVAMGG QSSTLADTKS LASQDFIRTA AIMLIGIALA LVFVTRSLLQ PVYIIGTLMI
AYMTSLSLTR WLTHLILGRD MLTWNTPFFS FIMLIALGVD YSIFLMMKYR EFGRDNMMPS
KRIVKSAGII GTVVISAAII LCGTFAALIP SGVPTLIEVA MAVIIGLIIL VFIIPIMIPS
TIRLTYPVKS GFQDAEKRED DNKKK
//
