ID   A0A0A1TQY9_9HYPO        Unreviewed;       395 AA.
AC   A0A0A1TQY9;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Peroxisomal membrane protein PEX14 {ECO:0000256|ARBA:ARBA00029502, ECO:0000256|RuleBase:RU367032};
DE   AltName: Full=Peroxin-14 {ECO:0000256|ARBA:ARBA00029691, ECO:0000256|RuleBase:RU367032};
GN   ORFNames=VHEMI09752 {ECO:0000313|EMBL:CEJ94208.1};
OS   [Torrubiella] hemipterigena.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae;
OC   Clavicipitaceae incertae sedis; 'Torrubiella' clade.
OX   NCBI_TaxID=1531966 {ECO:0000313|EMBL:CEJ94208.1, ECO:0000313|Proteomes:UP000039046};
RN   [1] {ECO:0000313|EMBL:CEJ94208.1, ECO:0000313|Proteomes:UP000039046}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Horn F., Habel A., Scharf D.H., Dworschak J., Brakhage A.A., Guthke R.,
RA   Hertweck C., Linde J.;
RT   "Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus
RT   Verticillium hemipterigenum.";
RL   Genome Announc. 3:e01439-e01414(2015).
CC   -!- FUNCTION: Component of the PEX13-PEX14 docking complex, a translocon
CC       channel that specifically mediates the import of peroxisomal cargo
CC       proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms
CC       a large import pore which can be opened to a diameter of about 9 nm.
CC       Mechanistically, PEX5 receptor along with cargo proteins associates
CC       with the PEX14 subunit of the PEX13-PEX14 docking complex in the
CC       cytosol, leading to the insertion of the receptor into the organelle
CC       membrane with the concomitant translocation of the cargo into the
CC       peroxisome matrix. {ECO:0000256|RuleBase:RU367032}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane
CC       {ECO:0000256|RuleBase:RU367032}.
CC   -!- SIMILARITY: Belongs to the peroxin-14 family.
CC       {ECO:0000256|ARBA:ARBA00005443, ECO:0000256|RuleBase:RU367032}.
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DR   EMBL; CDHN01000006; CEJ94208.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A1TQY9; -.
DR   STRING; 1531966.A0A0A1TQY9; -.
DR   HOGENOM; CLU_045718_0_0_1; -.
DR   OrthoDB; 72231at2759; -.
DR   Proteomes; UP000039046; Unassembled WGS sequence.
DR   GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016560; P:protein import into peroxisome matrix, docking; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR025655; PEX14.
DR   InterPro; IPR006785; Pex14_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23058; PEROXISOMAL MEMBRANE PROTEIN PEX14; 1.
DR   PANTHER; PTHR23058:SF0; PEROXISOMAL MEMBRANE PROTEIN PEX14; 1.
DR   Pfam; PF04695; Pex14_N; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367032};
KW   Peroxisome {ECO:0000256|ARBA:ARBA00023140, ECO:0000256|RuleBase:RU367032};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|RuleBase:RU367032};
KW   Reference proteome {ECO:0000313|Proteomes:UP000039046};
KW   Translocation {ECO:0000256|ARBA:ARBA00023010};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU367032}.
FT   DOMAIN          67..110
FT                   /note="Peroxisome membrane anchor protein Pex14p N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04695"
FT   REGION          311..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        340..375
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   395 AA;  43054 MW;  6763E8436617ACF6 CRC64;
     MLLRTELPRP VLASGRILHN YRAHAAHVRL VPAVEASSPS SFTIPIDRFP SSAELYPLST
     SPTMAIREEL VASATQFLQD PSVASSSVEN RITFLRSKNL TQEEIDVAMS RTGAGPPPPP
     PGASPYANAV GPAQPYYQPY SQYAWQPPPQ IPRRDWRDWF IMATVVSGVS YGLYSLGKRY
     VYPLVAPPTP EKLEQDKQHI SDQFDRAFNL VEQLAKDTED LKKTEQLRSE KLDTALTELE
     TVMAELKTAN RRRDDDALRI RDEIQALKDA IPKAMEGQKK ATDNRLYEIN TELTSLKTII
     SQRMATASKI ATTTPASPAA PASPAVPSPK VEDAPETPEP AAASTSSEPP KTLAQGAYNK
     TTRLSGSSGK PSIPAWQVAM ANKNNATAEG SSSSS
//