ID   A0A0A1TXI5_ENTIV        Unreviewed;       490 AA.
AC   A0A0A1TXI5;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Signal recognition particle receptor alpha subunit, putative {ECO:0000313|EMBL:ELP84230.1};
GN   ORFNames=EIN_064650 {ECO:0000313|EMBL:ELP84230.1};
OS   Entamoeba invadens IP1.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP84230.1, ECO:0000313|Proteomes:UP000014680};
RN   [1] {ECO:0000313|EMBL:ELP84230.1, ECO:0000313|Proteomes:UP000014680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP1 {ECO:0000313|EMBL:ELP84230.1,
RC   ECO:0000313|Proteomes:UP000014680};
RA   Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004397}.
CC   -!- SIMILARITY: Belongs to the GTP-binding SRP family.
CC       {ECO:0000256|ARBA:ARBA00008531}.
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DR   EMBL; KB207140; ELP84230.1; -; Genomic_DNA.
DR   RefSeq; XP_004183576.1; XM_004183528.1.
DR   AlphaFoldDB; A0A0A1TXI5; -.
DR   EnsemblProtists; ELP84230; ELP84230; EIN_064650.
DR   GeneID; 14883291; -.
DR   KEGG; eiv:EIN_064650; -.
DR   VEuPathDB; AmoebaDB:EIN_064650; -.
DR   OrthoDB; 5475029at2759; -.
DR   Proteomes; UP000014680; Unassembled WGS sequence.
DR   GO; GO:0005785; C:signal recognition particle receptor complex; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005047; F:signal recognition particle binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   CDD; cd14826; SR_alpha_SRX; 1.
DR   CDD; cd17876; SRalpha_C; 1.
DR   Gene3D; 3.30.450.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.20.120.140; Signal recognition particle SRP54, nucleotide-binding domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR007222; Sig_recog_particle_rcpt_asu_N.
DR   InterPro; IPR013822; Signal_recog_particl_SRP54_hlx.
DR   InterPro; IPR036225; SRP/SRP_N.
DR   InterPro; IPR000897; SRP54_GTPase_dom.
DR   InterPro; IPR042101; SRP54_N_sf.
DR   PANTHER; PTHR43134; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR43134:SF1; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR   Pfam; PF04086; SRP-alpha_N; 1.
DR   Pfam; PF00448; SRP54; 1.
DR   Pfam; PF02881; SRP54_N; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00962; SRP54; 1.
DR   SUPFAM; SSF47364; Domain of the SRP/SRP receptor G-proteins; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF64356; SNARE-like; 1.
DR   PROSITE; PS00300; SRP54; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:ELP84230.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT   DOMAIN          463..476
FT                   /note="SRP54-type proteins GTP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00300"
SQ   SEQUENCE   490 AA;  54732 MW;  B7C9FC237497824B CRC64;
     MEEICVVTTG GIVLYSKKYS EVRGEPVNTM IKEYILADRS GECKANIENY QVHWVTNVET
     STLFIAVHMK TIKVDYCERM LSDIEAKYRD EYLPSKHILK ERIEAIVVNS LKESQEWSRQ
     EKQNKKMRTF AETEKGVEIA QKLKKEKNEK SDKHEEKVVT SEGDGTKYTF AEMSKKDLRA
     KPQENQLQKW ISGFKGTRVV DEGEATQQAE NMEKLLIEKN VNSEVASQIK SNIHTLLLGK
     KVDTFTLRGT VIQGVTEVLT RIMTPSNVID VAKEIEEKKS KGEVFTMVFI GVNGVGKSTS
     LSKMACWLTS LNYKVMIAAC DTFRAGAVDQ LAVHAQRLGI PLYEKGYDTD PSAIARNALK
     RAKEDGYDVL LVDTAGRMQG NDALMKAIAK LVHSAQTDLV LFVAEALVGN DAVNQLTTFN
     RYVIDYAPVK TTKGVSGIIL TKFDTIDDKV GAAISLTYCT GIPILFVGTG QHYTDLKLLN
     VQDLIDSLLK
//