ID A0A0A1U2W2_ENTIV Unreviewed; 858 AA.
AC A0A0A1U2W2;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Leucine-rich repeat containing protein, putative {ECO:0000313|EMBL:ELP87008.1};
DE EC=3.1.3.16 {ECO:0000313|EMBL:ELP87008.1};
GN ORFNames=EIN_318770 {ECO:0000313|EMBL:ELP87008.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP87008.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP87008.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP87008.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
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DR EMBL; KB206890; ELP87008.1; -; Genomic_DNA.
DR RefSeq; XP_004253779.1; XM_004253731.1.
DR AlphaFoldDB; A0A0A1U2W2; -.
DR EnsemblProtists; ELP87008; ELP87008; EIN_318770.
DR GeneID; 14885886; -.
DR KEGG; eiv:EIN_318770; -.
DR VEuPathDB; AmoebaDB:EIN_318770; -.
DR OrthoDB; 22474at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF1; ZGC:77287; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00364; LRR_BAC; 9.
DR SMART; SM00365; LRR_SD22; 7.
DR SMART; SM00369; LRR_TYP; 12.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51450; LRR; 8.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000014680};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 614..858
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 858 AA; 95599 MW; 6867895B790A3B4C CRC64;
MAEAKIVKHA KNLIEFPSEE VKKEIKNLVS IDISMNRIQE LPSQVNSIPK LQKLRANDNM
IKTLPNQINI PTLKTLDLSS NHLKKFSKSI KLTSLTELNM SINQITKISD EFGTMQALRY
IDMSINRILA IPKHMSKLSN LTFIDVSNNL LSNFPTPLLE LTGLVVLKVK DNKIATTPNG
MSKMASLQIL DISNNRIDKI TPSLCKLTKL SVLDVSANPV NEINDQISSL TTIKEIDFSY
SLLKTLPKSF MLLTGLRKLT LQHTSVKVPP SGLQKFIKVS ELNLSNGELE KVTELPISGD
VDLSNNQIVE IDLPEMEYTI HRLNLSNNKL KEFPNIKKLS VIKTLIIPKN MLGSVPEEMF
TGTSLTELDL SSNSFNAFPM AITTCTNLVC LNMSNNYLDS LPDISYSCFA KLEELLLGIN
IIDRLPDTMS ELTNLTSLHL EHNKLSKIPE SLFSMGKLIE LFLNCNQIPE LPEKFSLLTN
LETLELSCNF IKDVTPITNL VAIKDLDLST NEIFDCPIKI CAMTSLRTLD LSYNGDFSST
ENFPMFFAST LTRLTNFHCT INDKVKLNKF ASTLKTPITG PVPFKAQNPT EHFSLGKPNS
MRFNNVAISN DTFTFGSAEM CGNRDQMEDA LILIENFTAG GVHLIGLFDG HGGAESSNYV
ACHFARILKK HLLTENNLGV DAALIETFNE LTADVNKKEF NDGTTACVLL VTPNEYYTAH
VGDSRAIVVR KQDHEQLTED DKATAPSEIE RIVSVGGYVT KGRVNGVLAI TRSIGDVRFQ
PFVSSEPHVN RYVRRKDTDM CIVMGCDGVW DVLTNEKVAD ICRKKEGTKR MSEIAGYIRD
MAFILGSEDN ISCVVCHF
//
