ID A0A0A1U400_ENTIV Unreviewed; 517 AA.
AC A0A0A1U400;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=ATP-dependent DNA helicase recQ, putative {ECO:0000313|EMBL:ELP88968.1};
GN ORFNames=EIN_491570 {ECO:0000313|EMBL:ELP88968.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP88968.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP88968.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP88968.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; KB206684; ELP88968.1; -; Genomic_DNA.
DR RefSeq; XP_004255739.1; XM_004255691.1.
DR AlphaFoldDB; A0A0A1U400; -.
DR SMR; A0A0A1U400; -.
DR EnsemblProtists; ELP88968; ELP88968; EIN_491570.
DR GeneID; 14887946; -.
DR KEGG; eiv:EIN_491570; -.
DR VEuPathDB; AmoebaDB:EIN_491570; -.
DR OrthoDB; 5474026at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELP88968.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 44..218
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 234..393
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 463..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 59110 MW; 641250080E5A4346 CRC64;
MFRPLFQTKT KPINAAVRYD KKLDDVLHNT FHIADFRPQQ RDIILSTLNN TDTVVIMPTG
GGKSLCFQLQ SVLTNKITIV ISPLISLMQN HVDALNARGV VSYIFNSSLT KSEASRVLAI
LNSTSPELYL LYVTPEQIKT QRFQNIMNKL NDNGKIGLFA IDEAHCISQW GHDFRPSYLE
LSYLKQTFPQ IPVIALTATA TEKVKDDIIK ALGLKDPNIF TSTFDRPNIY FRVLYKDLYE
NPQEELLKYL TQHQQEGGIV YCSTRNECEL LEKYLKSKGF RVGKYHAGMS ASDRESVQKM
WERKETGIVI ATVAFGMGID RSDVRFVVHW NIPKNIEGFI QEAGRAGRDG KPAESVIFFG
NDDFSRDKAL EGEKSEEIRE LCVECVCRRK CILKHFCETL ERKNERCCDL CNEMGRVKED
LEKVKIKLSR GNTRTTTKPL TIKNPEFKTA SVITENERTN SFQSASQLLE KQKHAKRENR
SIEKKECESK PRKCKGDEGL KSNATKITDF FGQKKKK
//
