GenomeNet

Database: UniProt
Entry: A0A0A2ECH6_9PORP
LinkDB: A0A0A2ECH6_9PORP
Original site: A0A0A2ECH6_9PORP 
ID   A0A0A2ECH6_9PORP        Unreviewed;       454 AA.
AC   A0A0A2ECH6;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   05-JUL-2017, entry version 21.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=HQ47_05560 {ECO:0000313|EMBL:KGN74139.1};
OS   Porphyromonas macacae.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales;
OC   Porphyromonadaceae; Porphyromonas.
OX   NCBI_TaxID=28115 {ECO:0000313|EMBL:KGN74139.1, ECO:0000313|Proteomes:UP000030103};
RN   [1] {ECO:0000313|EMBL:KGN74139.1, ECO:0000313|Proteomes:UP000030103}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COT-192 OH2859 {ECO:0000313|Proteomes:UP000030103};
RA   Wallis C., Deusch O., O'Flynn C., Davis I., Horsfall A., Kirkwood N.,
RA   Harris S., Eisen J.A., Coil D.A., Darling A.E., Jospin G., Alexiev A.;
RT   "Draft Genome Sequence of Porphyromonas macacae COT-192_OH2859.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGN74139.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; JRFA01000015; KGN74139.1; -; Genomic_DNA.
DR   RefSeq; WP_025003463.1; NZ_JRFA01000015.1.
DR   EnsemblBacteria; KGN74139; KGN74139; HQ47_05560.
DR   Proteomes; UP000030103; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030103};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030103}.
FT   DOMAIN      150    284       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      362    431       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     158    165       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   454 AA;  51689 MW;  57DC1F026F9A20B1 CRC64;
     MSKRNSLETL WQECLTSLRL LTDEKSYETW FAPIEAVNLQ NGALTLRVPT EYFSQYLESR
     YAAELSRVLG EHIGPHASLY FTYTTNPEVD KKATENNLPT GSPQTKEEEK KTFNSHLNEK
     LSFETFYESD CNHVARAVAE AVAAKPGNAP MNPYFIYGPS GVGKTHLSQA IGLRVKTLHP
     ELRVLYVSSQ EFEAQYVTSS RFHERTDFIH FYQQIDVLIV DDIQGLIGKV KTQQAFFEVF
     NHLKLLNKQI VLTSDKAPIH LSGMEERLIS RIKGSVTVAL DKPDIDLRRK ILKEKVAESG
     VKLKDEVIEF IAENVQNNVR ELEGTLCSLL TYALIAPDKE IDLTFTRNIV SRAVSLEKPE
     ITMERIQDVV TDVFHVDAGL IKDKTRRQDV VAARHAVMYL AKSYTNQSLN AIGEMLGRRN
     HATVLHGYNT VKDRMKVDQN FRQTMEKAIE RLHV
//
DBGET integrated database retrieval system