ID A0A0A2F017_9PORP Unreviewed; 434 AA.
AC A0A0A2F017;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Hemolysin {ECO:0000313|EMBL:KGN84368.1};
GN ORFNames=HQ41_04850 {ECO:0000313|EMBL:KGN84368.1};
OS Porphyromonas sp. COT-290 OH860.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=1515615 {ECO:0000313|EMBL:KGN84368.1, ECO:0000313|Proteomes:UP000030116};
RN [1] {ECO:0000313|EMBL:KGN84368.1, ECO:0000313|Proteomes:UP000030116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COT-290 OH860 {ECO:0000313|Proteomes:UP000030116};
RA Wallis C., Deusch O., O'Flynn C., Davis I., Jospin G., Darling A.E.,
RA Coil D.A., Alexiev A., Horsfall A., Kirkwood N., Harris S., Eisen J.A.;
RT "Porphyromonas sp. strain:COT-290_OH860 Genome sequencing.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGN84368.1}.
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DR EMBL; JRAR01000044; KGN84368.1; -; Genomic_DNA.
DR RefSeq; WP_044188567.1; NZ_JRAR01000044.1.
DR AlphaFoldDB; A0A0A2F017; -.
DR eggNOG; COG1253; Bacteria.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000030116; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR019862; Motility-assoc_prot_GldE.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR NCBIfam; TIGR03520; GldE; 1.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF17; UPF0053 INNER MEMBRANE PROTEIN YFJD; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000030116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..201
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 283..340
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 434 AA; 49134 MW; 2CD27EEB67645750 CRC64;
MADPILYDII SPNIPIGAWV ALAIGAGLLF ASGFMSSSEV AFFSLRPAEL DDVRRGEHPA
DEALYRLLSD PERLLATILI GNNLVNIAIV ILMGYGFSLI FDFSDAMILG FIFQTVILTL
LLLLFGEIIP KVYAQSNPLG FSRISAPYMR LVDKLLRPCS SFLVRSTKII TKRMQRKRYD
ISMDDLSQAV DLLNDKKVEE KTMFEEIISF YGKTASEIMV PRIDMLDIDI SWDFHRMLQF
ALDCGYSRIP VYETSEDNIR GIIYVKDLIL HKDKPADFQW TGLLRPAYFV PENKPLDDLL
EELRSNKIHM AIVVDEYGGT SGLVTMEDIL EEIVGNISDE YDEEELPYKK QADGSYLFEA
KTPLGDVLRY LDLEPGTFGK CEEEVDTLGG LYLEIKQDLP RLQDTVQAGA WSLRITELEK
FRIITIQLIP PTAP
//
