GenomeNet

Database: UniProt
Entry: A0A0A2FUN0_9PORP
LinkDB: A0A0A2FUN0_9PORP
Original site: A0A0A2FUN0_9PORP 
ID   A0A0A2FUN0_9PORP        Unreviewed;       124 AA.
AC   A0A0A2FUN0;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=Large ribosomal subunit protein bL12 {ECO:0000256|HAMAP-Rule:MF_00368};
GN   Name=rplL {ECO:0000256|HAMAP-Rule:MF_00368,
GN   ECO:0000313|EMBL:SQH72420.1};
GN   ORFNames=HQ45_06525 {ECO:0000313|EMBL:KGN89650.1}, NCTC12858_00235
GN   {ECO:0000313|EMBL:SQH72420.1};
OS   Porphyromonas crevioricanis.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC   Porphyromonas.
OX   NCBI_TaxID=393921 {ECO:0000313|EMBL:KGN89650.1, ECO:0000313|Proteomes:UP000030139};
RN   [1] {ECO:0000313|EMBL:KGN89650.1, ECO:0000313|Proteomes:UP000030139}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COT-253 OH2125 {ECO:0000313|Proteomes:UP000030139}, and
RC   COT-253_OH2125 {ECO:0000313|EMBL:KGN89650.1};
RA   Wallis C., Deusch O., O'Flynn C., Davis I., Jospin G., Darling A.E.,
RA   Coil D.A., Alexiev A., Horsfall A., Kirkwood N., Harris S., Eisen J.A.;
RT   "Porphyromonas crevioricanis strain:COT-253_OH2125 Genome sequencing.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:SQH72420.1, ECO:0000313|Proteomes:UP000249300}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC12858 {ECO:0000313|EMBL:SQH72420.1,
RC   ECO:0000313|Proteomes:UP000249300};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC       interact with GTP-bound translation factors. Is thus essential for
CC       accurate translation. {ECO:0000256|HAMAP-Rule:MF_00368}.
CC   -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC       subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC       elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC       fashion. Binds GTP-bound translation factors. {ECO:0000256|HAMAP-
CC       Rule:MF_00368}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC       {ECO:0000256|ARBA:ARBA00007197, ECO:0000256|HAMAP-Rule:MF_00368}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JQJB01000008; KGN89650.1; -; Genomic_DNA.
DR   EMBL; LS483447; SQH72420.1; -; Genomic_DNA.
DR   RefSeq; WP_023936394.1; NZ_LS483447.1.
DR   AlphaFoldDB; A0A0A2FUN0; -.
DR   STRING; 393921.HQ45_06525; -.
DR   KEGG; pcre:NCTC12858_00235; -.
DR   eggNOG; COG0222; Bacteria.
DR   OrthoDB; 9811748at2; -.
DR   Proteomes; UP000030139; Unassembled WGS sequence.
DR   Proteomes; UP000249300; Chromosome 1.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00387; Ribosomal_L7_L12; 1.
DR   Gene3D; 3.30.1390.10; -; 1.
DR   Gene3D; 1.20.5.710; Single helix bin; 1.
DR   HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR   InterPro; IPR000206; Ribosomal_bL12.
DR   InterPro; IPR013823; Ribosomal_bL12_C.
DR   InterPro; IPR014719; Ribosomal_bL12_C/ClpS-like.
DR   InterPro; IPR008932; Ribosomal_bL12_oligo.
DR   InterPro; IPR036235; Ribosomal_bL12_oligo_N_sf.
DR   NCBIfam; TIGR00855; L12; 1.
DR   PANTHER; PTHR45987; 39S RIBOSOMAL PROTEIN L12; 1.
DR   PANTHER; PTHR45987:SF4; 39S RIBOSOMAL PROTEIN L12, MITOCHONDRIAL; 1.
DR   Pfam; PF00542; Ribosomal_L12; 1.
DR   Pfam; PF16320; Ribosomal_L12_N; 1.
DR   SUPFAM; SSF54736; ClpS-like; 1.
DR   SUPFAM; SSF48300; Ribosomal protein L7/12, oligomerisation (N-terminal) domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000249300};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW   Rule:MF_00368};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW   Rule:MF_00368}.
FT   DOMAIN          4..51
FT                   /note="Large ribosomal subunit protein bL12
FT                   oligomerization"
FT                   /evidence="ECO:0000259|Pfam:PF16320"
FT   DOMAIN          58..124
FT                   /note="Large ribosomal subunit protein bL12 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00542"
SQ   SEQUENCE   124 AA;  12636 MW;  9DA767CF9CB1A4F4 CRC64;
     MADIKAIAEQ LVNLTVKEVS ELATVLKEEY GIEPAAAAVA VAAPGAGAAA AEEEKTSFDV
     VLKSPGGAKL QVVKAVKEHC GLGLKEAKDL VDAAPSNVKE GVDKATAEAL KKALEEAGAE
     VELK
//
DBGET integrated database retrieval system