ID A0A0A2JG46_PENEN Unreviewed; 834 AA.
AC A0A0A2JG46;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=6-phosphogluconate dehydrogenase NADP-binding domain-containing protein {ECO:0000259|Pfam:PF03446};
GN ORFNames=PEX2_062490 {ECO:0000313|EMBL:KGO53638.1};
OS Penicillium expansum (Blue mold rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=27334 {ECO:0000313|EMBL:KGO53638.1, ECO:0000313|Proteomes:UP000030143};
RN [1] {ECO:0000313|EMBL:KGO53638.1, ECO:0000313|Proteomes:UP000030143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-8 {ECO:0000313|EMBL:KGO53638.1,
RC ECO:0000313|Proteomes:UP000030143};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO53638.1}.
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DR EMBL; JQFZ01000248; KGO53638.1; -; Genomic_DNA.
DR RefSeq; XP_016596227.1; XM_016743520.1.
DR AlphaFoldDB; A0A0A2JG46; -.
DR STRING; 27334.A0A0A2JG46; -.
DR GeneID; 27678940; -.
DR HOGENOM; CLU_009650_2_2_1; -.
DR OrthoDB; 2204710at2759; -.
DR Proteomes; UP000030143; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR021822; DUF3405.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR36205:SF4; -; 1.
DR PANTHER; PTHR36205; CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE; 1.
DR Pfam; PF11885; DUF3405; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030143};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 587..664
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT REGION 166..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 94810 MW; 47D1F5EA5744FB98 CRC64;
MLFKGTDLAL QKLSMVLVAS FVFVVILLRP QINEHILPLR LWKDGHDSTS RPIPYNPYPD
YNSAAWKRKW RGSYQQCVGP DGALLDPKNE DMAMKGYRWK QSEFPTPIFG SYEAWHLDRD
LCVDLSSRYG TYGYEVKTRD GVASRISRNW EGVNWAELQR ACLGSNRERY NKSNPEPKKS
TLHKQQTQQV EYRHKKHRHR KSRLPQFHLR KAVILRSTID MKYTTNDIHN IRAMVMEHSL
LSGAEYEVIL LIDAKDEILP EPMDNVAMDS FKEEYLPKEL RGLAVFFNTK LLEDWYPTID
VHEAMYQYFQ PVQIFSLLYQ QYDFIWQFEM DARYTGHLYH LLEQATAFAK QQPRKHLWER
NSYFYIPKVH GTWDEFNKMV DQSMVDRPTV WGPVLAKGLN VSKEAPFPAP TPTAEIDRSR
WGVGEEPDVI TWLPQFNPAS TGWPMRDVIY EFIEGQSTPR RASPVAMSRL LARVLRLMHT
DLVDNGLALG SEMSPTSWAL YYGLKSVQIP QPVYHAQEWD LEELNRRANS GEPGAISVRS
DSIWTWNMHH DILKNMTYMF DSEYSGRLYR AWLGDGNVEE TSDDAALNAI VDEILAVKDI
DDKLFVDTTT VHPNTTKETD EKLKNRNASF VAAPVFGATP AAESGTVLMA MAGPSPAIDK
LAPFGKGVIA RDVMIVSDQP EKATLLKTLG NFLVAGTMEI VGEAQVLAEK SDLGTGMLEK
LLELNFGSLM HSSSRRMTQG VYLPEEGQSP WSNLNLGIKD VQHGISCAQN VGARLKVAEV
ALENMSRAKD FSDAHGGRPL DSSSGYGVIR QDSGLDFENA FVKERDTRKE NGSS
//
