ID   A0A0A2JVU3_PENEN        Unreviewed;       811 AA.
AC   A0A0A2JVU3;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Monooxygenase, FAD-binding {ECO:0000313|EMBL:KGO59534.1};
GN   ORFNames=PEX2_075140 {ECO:0000313|EMBL:KGO59534.1};
OS   Penicillium expansum (Blue mold rot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=27334 {ECO:0000313|EMBL:KGO59534.1, ECO:0000313|Proteomes:UP000030143};
RN   [1] {ECO:0000313|EMBL:KGO59534.1, ECO:0000313|Proteomes:UP000030143}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MD-8 {ECO:0000313|EMBL:KGO59534.1,
RC   ECO:0000313|Proteomes:UP000030143};
RX   PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA   Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA   Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT   "Genome, transcriptome, and functional analyses of Penicillium expansum
RT   provide new insights into secondary metabolism and pathogenicity.";
RL   Mol. Plant Microbe Interact. 28:232-248(2015).
CC   -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC       {ECO:0000256|ARBA:ARBA00007992}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGO59534.1}.
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DR   EMBL; JQFZ01000094; KGO59534.1; -; Genomic_DNA.
DR   RefSeq; XP_016600704.1; XM_016744784.1.
DR   AlphaFoldDB; A0A0A2JVU3; -.
DR   STRING; 27334.A0A0A2JVU3; -.
DR   GeneID; 27680204; -.
DR   HOGENOM; CLU_009665_12_0_1; -.
DR   OrthoDB; 2332834at2759; -.
DR   Proteomes; UP000030143; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR47356:SF2; FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR47356; FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED; 1.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Monooxygenase {ECO:0000313|EMBL:KGO59534.1};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030143};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        450..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        607..629
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        641..660
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        681..701
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          8..344
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
SQ   SEQUENCE   811 AA;  90628 MW;  5640A93A1C276693 CRC64;
     MQPNPKFRVI IVGGSVAGLT LAHCLLKNNI DFVVLEASPE VAPEVGASLG LLANGGRILD
     QLGVYDDVQA EVVSIEDAYF WAADGSLMLK SNSPDELNKR HGYPIAFLPR RTLLKILLKH
     LGDRQDDVVP NKKVIRVDHY PSHVIVHCAD GSSYEGDMVV GADGVRSVVR QSMWDYMESQ
     GLKSEVQKER STMSAEYNCV FGMSTATPGL DPKDIHRTFG KDWSFLTIAG KGNKSYWFLY
     NKMDRTYYGS DIPRFNKADI DERVAPYLHR PVTDSVPFSE LYKRSTIRTF VALEEANFNH
     WCIDRFACIG DSIHKMTPNI GQGGNSAIES SATLANHLAR LLQRSSPYQT EDINRCTQAW
     QASRRDRVDK ICREAFNLTR LEAIASPKYR LMIYLIPYMK TKMIEKTSAT LVASPKLECA
     PETVKALWCS IPYKTEKPAS EATETIWERV LWGMPFLGCF AVASATMGAI LTKVRQLMIP
     YFIQGTWRST NGEVLDIRKA VYHIPFLDNL LRPMITCFLP SISGSDLQSR AQMISFLADL
     GAVYGIWLLE SYRKANGWSE VAIPISICSV FQLKGIGLLA PIYYLLEYVR TPLSKLLPKN
     MREVEPTGSI SLLAAMLIGH YFPTFASFTA PTLDSRRWWN AMWQIFPITV PLIQLPFALL
     GKRLLPSTKA SPEEKSQNSM TSTRIAYGGF ALISALTFIY ARCSAPADAS LLSIFWPGFS
     SHHLPVTSFQ EGIARFLQYD QVLSMGSGFF WLALRFREIK QSGGSVSWWK AIGSLVATIS
     SFGPGTAFAL GWGWREELIH KLAISQGVCS E
//