ID A0A0A2K6B5_PENEN Unreviewed; 305 AA.
AC A0A0A2K6B5;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE SubName: Full=Ketopantoate reductase ApbA/PanE, C-terminal {ECO:0000313|EMBL:KGO63402.1};
GN ORFNames=PEX2_011910 {ECO:0000313|EMBL:KGO63402.1};
OS Penicillium expansum (Blue mold rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=27334 {ECO:0000313|EMBL:KGO63402.1, ECO:0000313|Proteomes:UP000030143};
RN [1] {ECO:0000313|EMBL:KGO63402.1, ECO:0000313|Proteomes:UP000030143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-8 {ECO:0000313|EMBL:KGO63402.1,
RC ECO:0000313|Proteomes:UP000030143};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO63402.1}.
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DR EMBL; JQFZ01000002; KGO63402.1; -; Genomic_DNA.
DR RefSeq; XP_016603822.1; XM_016738468.1.
DR AlphaFoldDB; A0A0A2K6B5; -.
DR STRING; 27334.A0A0A2K6B5; -.
DR GeneID; 27673887; -.
DR HOGENOM; CLU_031468_2_1_1; -.
DR OrthoDB; 1816688at2759; -.
DR Proteomes; UP000030143; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR21708:SF30; 2-REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00740)-RELATED; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030143}.
FT DOMAIN 2..148
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 183..303
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 305 AA; 34031 MW; 968F85278EFADEBB CRC64;
MLLIGAGGVG TMACVSLERS CIVLRSDYDK VMRDGFEIES ANHGIFSSWW PSRILKAVPQ
IQEVTYDHVM VTMKKIPEIS NISAVIKPAI TPGYTTIVLI QNGICIEQPI IDAFPSNVVL
SGVSYIGAHE RNGRILHDEH DHMNLGVFHN QALDVKIEQE KLHDFATIYS ANRAVSVDIA
GDFQFYRWRS VSWNGAFNSM CAITQLDSAD IRYLGGEYSL LRPGMAEMAA IAKADSYDLW
PDIVDFMINF TGLELSFRPS MLVDVDKGNP IEVEVILGNV LRVARKLDVL TPILDNTCRF
LKLIH
//
