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Database: UniProt
Entry: A0A0A2LEZ0_PENIT
LinkDB: A0A0A2LEZ0_PENIT
Original site: A0A0A2LEZ0_PENIT 
ID   A0A0A2LEZ0_PENIT        Unreviewed;       855 AA.
AC   A0A0A2LEZ0;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   16-MAR-2016, entry version 7.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=PITC_067890 {ECO:0000313|EMBL:KGO78489.1};
OS   Penicillium italicum (Blue mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=40296 {ECO:0000313|EMBL:KGO78489.1, ECO:0000313|Proteomes:UP000030104};
RN   [1] {ECO:0000313|EMBL:KGO78489.1, ECO:0000313|Proteomes:UP000030104}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PHI-1 {ECO:0000313|EMBL:KGO78489.1,
RC   ECO:0000313|Proteomes:UP000030104};
RX   PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA   Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA   Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L.,
RA   Gabaldon T.;
RT   "Genome, transcriptome, and functional analyses of Penicillium
RT   expansum provide new insights into secondary metabolism and
RT   pathogenicity.";
RL   Mol. Plant Microbe Interact. 28:232-248(2015).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGO78489.1}.
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DR   EMBL; JQGA01000005; KGO78489.1; -; Genomic_DNA.
DR   EnsemblFungi; KGO78489; KGO78489; PITC_067890.
DR   PhylomeDB; A0A0A2LEZ0; -.
DR   Proteomes; UP000030104; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030104};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030104};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    425    450       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    462    487       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    549    567       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    579    602       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    645    665       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    758    778       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    790    811       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED      100    127       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   855 AA;  97666 MW;  6176DAC7B8B1B3E4 CRC64;
     MAPRDTFFRS ADMSLTQLYI ANEIGREVVS ALGEVGQVQF RDLNPDTNAF QRTFTKEIRR
     LDNVERQLRY FHQQMEKAAI PMRSSSDFSD TLAAPLASEI DELADRSESL EQRIISLNDS
     YETLKKREVE LTEWRWVLRE AGGFFDRAHT QTEDIRQSFD NDEAPLLRDV EHHAPHQNGD
     TQGQQSFSEM NIGFVAGVIP RDRIGAFERI LWRTLRGNLY MNQSEIAEPI IDPMTNEEVH
     KNVFVIFAHG KNILAKIRKI SESLNASLYG VDENSELRRD QIHEVNTRLG DVGNVLRNTK
     NTLDAELSQI ARSLAAWMII VKKEKAVYDT LNKFSYDQAR KTLIAEAWCP TNSLTLIKST
     LQDVNDRAGL TVPTIVNQIR TNKTPPTFVR TNKFTEGFQT IVNAYGIPKY SEVNPGLYTV
     VTFPFLFAVM FGDCGHGALM TLAASAMIFW EKKLARTKLD ELTYMAFYGR YIMLMMGLFS
     IYTGFIYNDI FSKSFTIFPS QWQWPEDIKP NQMIEATLKE GYRYPIGLDW NWHEADNSLL
     FSNSMKMKMS VLLGWCHMTY ALCLQYVNGR HFKSKVDIWG NFVPGLLFFQ SIFGYLVLTI
     LYKWSVNWQE KGVNPPGLLN MLIFMFLSPG TVDEQLYPGQ SSVQVLLLLV AVAQVPIMLF
     LKPFWLRYEH NRARALGYRG LGENSRVSAL DADGDMGGGL GRDSLASDGE GVAMLSQDID
     DSEEHEEFDF GDIMIHQVIH TIEFCLNCIS HTASYLRLWA LSLAHQQLSI VLWTMTIGSA
     FDQENPVTRV IMIVVSFYLW FVLTICILCV MEGTSAMLHS LRLHWVEAMS KHFVGEGIPF
     LPFSFKTLLE EDPVD
//
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