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Database: UniProt
Entry: A0A0A2TVB6_9BACI
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ID   A0A0A2TVB6_9BACI        Unreviewed;       451 AA.
AC   A0A0A2TVB6;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   25-OCT-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=N782_06945 {ECO:0000313|EMBL:KGP73225.1};
OS   Pontibacillus yanchengensis Y32.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX   NCBI_TaxID=1385514 {ECO:0000313|EMBL:KGP73225.1, ECO:0000313|Proteomes:UP000030147};
RN   [1] {ECO:0000313|EMBL:KGP73225.1, ECO:0000313|Proteomes:UP000030147}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y32 {ECO:0000313|EMBL:KGP73225.1,
RC   ECO:0000313|Proteomes:UP000030147};
RX   PubMed=26561516; DOI=10.1186/s40793-015-0085-y;
RA   Huang J., Qiao Z.X., Tang J.W., Wang G.;
RT   "High quality draft genome sequence of the moderately halophilic
RT   bacterium Pontibacillus yanchengensis Y32(T) and comparison among
RT   Pontibacillus genomes.";
RL   Stand. Genomic Sci. 10:93-93(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGP73225.1}.
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DR   EMBL; AVBF01000016; KGP73225.1; -; Genomic_DNA.
DR   RefSeq; WP_036818179.1; NZ_AVBF01000016.1.
DR   EnsemblBacteria; KGP73225; KGP73225; N782_06945.
DR   Proteomes; UP000030147; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030147};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030147}.
FT   DOMAIN      146    274       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      358    427       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     154    161       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      420    451       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   451 AA;  51109 MW;  BBBF3F814A619CEA CRC64;
     MENIKELWDN TLSQIEEKIS KPSFETWLKS TKADSLKDDT LVIVAPNEFA RDWLESRYAN
     LIADTLYEVT GAQLRTKFII PETKEESVDD VKPAIKQSSN NKDSDQEESP QSMLNSKYTF
     DTFVIGSGNR FAHAASLAVA EAPAKAYNPL FIYGGVGLGK THLMHAIGHY VLDHNPSAKV
     VYLSSEKFTN EFINSIRDNK AVNFRNKYRN VDVLLIDDIQ FLAGKEQTQE EFFHTFNTLH
     EENKQIVISS DRPPKEIPTL EDRLRSRFEW GLITDITPPD LETRIAILRK KAKAEGLDIP
     NEVMLYIANQ IDTNIRELEG ALIRVVAYSS LINRDIDASL AAEALKDIIP SSKPKIITIK
     GIQEMVAEKY NIKVEDFAAK KRTKTIAHPR QIAMYLSREM TDFSLPKIGE EFGGRDHTTV
     IHAHEKISKA LSENQQLQNE IEELKEALKS G
//
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