ID   A0A0A5G5M4_9BACI        Unreviewed;       350 AA.
AC   A0A0A5G5M4;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Butanediol dehydrogenase {ECO:0000313|EMBL:KGX87359.1};
GN   ORFNames=N784_15775 {ECO:0000313|EMBL:KGX87359.1};
OS   Pontibacillus litoralis JSM 072002.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX   NCBI_TaxID=1385512 {ECO:0000313|EMBL:KGX87359.1, ECO:0000313|Proteomes:UP000030401};
RN   [1] {ECO:0000313|EMBL:KGX87359.1, ECO:0000313|Proteomes:UP000030401}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JSM 072002 {ECO:0000313|EMBL:KGX87359.1,
RC   ECO:0000313|Proteomes:UP000030401};
RA   Huang J., Wang G.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGX87359.1}.
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DR   EMBL; AVPG01000007; KGX87359.1; -; Genomic_DNA.
DR   RefSeq; WP_036833533.1; NZ_AVPG01000007.1.
DR   AlphaFoldDB; A0A0A5G5M4; -.
DR   STRING; 1385512.N784_15775; -.
DR   eggNOG; COG1063; Bacteria.
DR   OrthoDB; 9770238at2; -.
DR   Proteomes; UP000030401; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08233; butanediol_DH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43161:SF23; (R,R)-BUTANEDIOL DEHYDROGENASE-RELATED; 1.
DR   PANTHER; PTHR43161; SORBITOL DEHYDROGENASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030401};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          8..345
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   350 AA;  37517 MW;  5F6404A22CA6BC7C CRC64;
     MKAAVWYGKN DLRVENVEEP VIQPGKVKVK VAFAGICGSD LHAYHGADVI QQGTPHPVTG
     VMAPLTMGHE FSGVITEVGE GVDNVSVGDR VAIEPLIYCG ECEHCKNNNY NLCDNSGFIG
     LHDNGGFAEY VTVEPHFVHK LPDNLSLEQG ALIEPAAVAF HAVKQSNMKI GNKVAVFGVG
     PIGLLTIIAA QAAGASEIYA IDVSSERLQK AKEVGATRTI NAMEEDAIKT ILSQAPGGVD
     VAYEVAGVEA TLANALSVIR KQGEVMVVSI IPEPIKIDMM QLTLKEAYLT SVLGYRHIYP
     EVISLVAAGK LDIEKVVTKK IKLENIVEDG MELLTHDKSQ AKILIDIQKS
//