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Database: UniProt
Entry: A0A0A6T2X9_9BURK
LinkDB: A0A0A6T2X9_9BURK
Original site: A0A0A6T2X9_9BURK 
ID   A0A0A6T2X9_9BURK        Unreviewed;       528 AA.
AC   A0A0A6T2X9;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   25-OCT-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=NH14_05175 {ECO:0000313|EMBL:KHD21901.1};
OS   Paraburkholderia sacchari.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=159450 {ECO:0000313|EMBL:KHD21901.1, ECO:0000313|Proteomes:UP000030460};
RN   [1] {ECO:0000313|EMBL:KHD21901.1, ECO:0000313|Proteomes:UP000030460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 19450 {ECO:0000313|EMBL:KHD21901.1,
RC   ECO:0000313|Proteomes:UP000030460};
RA   Alexandrino P., Mendonca T., Bautista L., Cherix J., Lozano G.,
RA   Fujita A., Filho E., Long P., Padilla G., Taciro M., Gomez J.,
RA   Silva L.;
RT   "Draft Genome Sequence of the Polyhydroxyalkanoate-producing Bacterium
RT   Burkholderia sacchari LMG 19450 Isolated from Brazilian Sugarcane
RT   Plantation Soil.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KHD21901.1}.
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DR   EMBL; JTDB01000003; KHD21901.1; -; Genomic_DNA.
DR   EnsemblBacteria; KHD21901; KHD21901; NH14_05175.
DR   Proteomes; UP000030460; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030460};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030460}.
FT   DOMAIN      225    359       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      436    505       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     233    240       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   528 AA;  58138 MW;  77B7FC1558659C6B CRC64;
     MNEFWQHCSA LLERELTPQQ YVTWIKPLAP VAFDAAANTL QIAAPNRFKL DWVKSQFSGR
     ITDLARDFWQ LPVDVQFVLD PKAGMRAPQA ASAPAPRAPL AAAMQAEAAH VAAHVASQAV
     MSQTSPGAAA LAGLAGMSHA AAQATEDAAD LDLPSLDANE AAAGRRGWRP GQSAAAAAAA
     NGEPDPTYER SKLNPVLTFD NFVTGKANQL ARAAAIQVAD NPGISYNPLF LYGGVGLGKT
     HLIHAIGNQL LIDKPGARIR YIHAEQYVSD VVKAYQRKAF DDFKRYYHSL DLLLIDDIQF
     FSGKSRTQEE FFYAFEALVA NKAQVIITSD TYPKEISGID DRLISRFDSG LTVAIEPPEL
     EMRVAILMRK AQSEGVSLNE DVAFFVAKHL RSNVRELEGA LRKILAYSKF HGREISIELT
     KEALKDLLTV QNRQISVENI QKTVADFYSI KVADMYSKKR PANIARPRQI AMYLAKELTQ
     KSLPEIGELF GGRDHTTVLH AVRKIADERT KDAQLNHELH VLEQTLKG
//
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