ID A0A0A6UDK8_ACTUT Unreviewed; 388 AA.
AC A0A0A6UDK8;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=ROK family transcriptional regulator {ECO:0000313|EMBL:KHD74130.1};
GN ORFNames=MB27_30540 {ECO:0000313|EMBL:KHD74130.1};
OS Actinoplanes utahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1869 {ECO:0000313|EMBL:KHD74130.1, ECO:0000313|Proteomes:UP000054537};
RN [1] {ECO:0000313|EMBL:KHD74130.1, ECO:0000313|Proteomes:UP000054537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 12052 {ECO:0000313|EMBL:KHD74130.1,
RC ECO:0000313|Proteomes:UP000054537};
RA Velasco-Bucheli B., del Cerro C., Hormigo D., Garcia J.L., Acebal C.,
RA Arroyo M., de la Mata I.;
RT "Draft genome sequence of Actinoplanes utahensis NRRL 12052.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHD74130.1}.
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DR EMBL; JRTT01000054; KHD74130.1; -; Genomic_DNA.
DR RefSeq; WP_043530273.1; NZ_JRTT01000054.1.
DR AlphaFoldDB; A0A0A6UDK8; -.
DR STRING; 1869.MB27_30540; -.
DR eggNOG; COG1940; Bacteria.
DR OrthoDB; 3534172at2; -.
DR Proteomes; UP000054537; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054537};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 318..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..58
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
SQ SEQUENCE 388 AA; 40032 MW; E33039B0B0236C76 CRC64;
MTEATRRRRP GARESILDAI RASEPLSRVE LAAITGLTEA AVSMTVRRLL EDGLLVETGR
TPTGGKPRTL LRLDPAARLA VGVYLDRDTT TYVLTGQTGG VISRLARPAP ADDLPAHLTD
GIGTLLAGSG VDPARCLGVG VVWPCTGSGI ARFDDAPPHL SGWDGDELGR RLTESTGWPV
LVENDATAAA VGEYWVARVG PQQAFAALYM GSGLGAGIIV EGRAMRGGHG TAGEFGHVCV
QVDGPECWCG SRGCLEVIAG PRTVVLAARA DPAIGLVPGR SIGADFAAIA RAARAGSPAC
LALLEESARY VAAAAESVVN LLDIDLVVLT GPGFAAASFV YGPAIMRRIQ PADARTWNRS
VTVTVSLAAA TASATGAAAL VLQSDLRR
//
