ID A0A0A6UGA9_ACTUT Unreviewed; 584 AA.
AC A0A0A6UGA9;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Copper resistance protein CopC {ECO:0000313|EMBL:KHD73329.1};
GN ORFNames=MB27_35780 {ECO:0000313|EMBL:KHD73329.1};
OS Actinoplanes utahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1869 {ECO:0000313|EMBL:KHD73329.1, ECO:0000313|Proteomes:UP000054537};
RN [1] {ECO:0000313|EMBL:KHD73329.1, ECO:0000313|Proteomes:UP000054537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 12052 {ECO:0000313|EMBL:KHD73329.1,
RC ECO:0000313|Proteomes:UP000054537};
RA Velasco-Bucheli B., del Cerro C., Hormigo D., Garcia J.L., Acebal C.,
RA Arroyo M., de la Mata I.;
RT "Draft genome sequence of Actinoplanes utahensis NRRL 12052.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHD73329.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JRTT01000132; KHD73329.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A6UGA9; -.
DR STRING; 1869.MB27_35780; -.
DR eggNOG; COG1276; Bacteria.
DR eggNOG; COG2372; Bacteria.
DR Proteomes; UP000054537; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR GO; GO:0046688; P:response to copper ion; IEA:InterPro.
DR Gene3D; 2.60.40.1220; -; 1.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR007348; CopC_dom.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF04234; CopC; 1.
DR Pfam; PF05425; CopD; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054537};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..584
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002033812"
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..114
FT /note="CopC"
FT /evidence="ECO:0000259|Pfam:PF04234"
FT DOMAIN 365..457
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
SQ SEQUENCE 584 AA; 59375 MW; 571DFF4D28A6E424 CRC64;
MLFLLLVITG LTVPASPASA HAAPVGSNPA PGSVIGSSPS EVTVTFSEPV APVAGHVQVI
APDGERISGT ATVSGNVVRI PVRKAERPLG TYLISFRVIS ADSHPVGGAI TFSVGAPSAR
PEAPAASTGP HSSVAVAVPL LKTLGYAGMT LIVGPALFLA FLWPRRRSRA GALRTVRIGV
VLSAVATAGA LGTQAQQGSG APLWRVSAAE LAEVATSQFG LLLLARLTVL AAVAVLLPPL
LRARTPARAA ATPVRLLAFA GTAPAPPAPS VPAPSVPAAS GAAATGAAAT RPAIGRVRGA
TVLLLAVAGL ATWPLTGHAV AVPLPAVTVA AGVVHMAAMA VWIGGLVTLA AFLLRGTNPR
VLGVILPVWS RWAALAVLWL VVAGLVHAVV QLGRVSALWE TDYGRLLAGK VAILAAVLAV
AAVARRLVVR RATGALRRLV GVEVAAAAVV LALSSLLVQV DPGRVQAARD RAITGAGTSE
TLTTDLYTVQ FNIYPVELGE YNTVHAFLYS PAGAPLRAEE WQLTARLTDP ALEAVPQPIA
GLETGNQALG SVSFPLPGTY ELTFTIRTTA LDRATVRTTV TVTG
//
