ID A0A0A6UNW3_ACTUT Unreviewed; 412 AA.
AC A0A0A6UNW3;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cobalamin biosynthesis protein P47K {ECO:0000313|EMBL:KHD77800.1};
GN ORFNames=MB27_08325 {ECO:0000313|EMBL:KHD77800.1};
OS Actinoplanes utahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1869 {ECO:0000313|EMBL:KHD77800.1, ECO:0000313|Proteomes:UP000054537};
RN [1] {ECO:0000313|EMBL:KHD77800.1, ECO:0000313|Proteomes:UP000054537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 12052 {ECO:0000313|EMBL:KHD77800.1,
RC ECO:0000313|Proteomes:UP000054537};
RA Velasco-Bucheli B., del Cerro C., Hormigo D., Garcia J.L., Acebal C.,
RA Arroyo M., de la Mata I.;
RT "Draft genome sequence of Actinoplanes utahensis NRRL 12052.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHD77800.1}.
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DR EMBL; JRTT01000008; KHD77800.1; -; Genomic_DNA.
DR RefSeq; WP_043523602.1; NZ_JRTT01000008.1.
DR AlphaFoldDB; A0A0A6UNW3; -.
DR STRING; 1869.MB27_08325; -.
DR eggNOG; COG0523; Bacteria.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000054537; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000054537}.
FT DOMAIN 262..377
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 412 AA; 45191 MW; E0B6DE7A96CF6D19 CRC64;
MSSTTTPERL PVTVLSGFLS AGKTTLLNHV LANRDGLRVA VIVNDMSEIN IDGALIRDGG
ALSRTEERLV EMTNGCICCT LRDDLLGEVA DLARQGRFDY LIIESSGISE PLPVAATFAL
GIDEQDRVLA DIARLDTMVT VVDAPHLIAQ INAGEALEAR GLAAFEDDDR TIADLLIDQL
EFADAIVINK TDLVTDVELA RVEALVTRLN PRARQIRSTF GRVSPADLLD TGSFDMAAAE
TAPGWVAELN GDHIPETIEY GIGSLLFRAA EPFHPQRLWD LLDTAVTDYG VLRSKGFLWL
ATRPGMIGLW SQAGPHGRCD PAGVPVAVSG EWPDDPEERA DLEQLWHPVF GDRRQELVFI
GVRLPAEELR EGLRRCLLTD EELAAGADTW QTWPDPFPQW ALDDMEPHAH QH
//
