ID A0A0A6X220_ACTUT Unreviewed; 447 AA.
AC A0A0A6X220;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=MB27_30400 {ECO:0000313|EMBL:KHD74147.1};
OS Actinoplanes utahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1869 {ECO:0000313|EMBL:KHD74147.1, ECO:0000313|Proteomes:UP000054537};
RN [1] {ECO:0000313|EMBL:KHD74147.1, ECO:0000313|Proteomes:UP000054537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 12052 {ECO:0000313|EMBL:KHD74147.1,
RC ECO:0000313|Proteomes:UP000054537};
RA Velasco-Bucheli B., del Cerro C., Hormigo D., Garcia J.L., Acebal C.,
RA Arroyo M., de la Mata I.;
RT "Draft genome sequence of Actinoplanes utahensis NRRL 12052.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHD74147.1}.
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DR EMBL; JRTT01000053; KHD74147.1; -; Genomic_DNA.
DR RefSeq; WP_043530210.1; NZ_JRTT01000053.1.
DR AlphaFoldDB; A0A0A6X220; -.
DR STRING; 1869.MB27_30400; -.
DR eggNOG; COG2205; Bacteria.
DR OrthoDB; 340764at2; -.
DR Proteomes; UP000054537; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:KHD74147.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054537};
KW Transferase {ECO:0000313|EMBL:KHD74147.1}.
FT DOMAIN 230..447
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 147..209
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 447 AA; 48452 MW; 40DF517ED074E226 CRC64;
MTAEPLMRMR LRVEQDIFVV RQLGREVARA VGLESQDQTR MATALSEVGR VLLASGRDTD
VAFSIEPIGV PTLLVTMAQP GAGTAIRLAG QLQLVGRLVD TMEVDDGSSG TVVRMARRLP
SGAPRLTPDR MDEIRDGLTQ HVPGTPLDEL AVQNQQLITA LDEVRAQRDD LARLNAELEE
TNRGVMALYN QLSQELEETN RGVVALYAEL DEKSAQLRAA SEAKSRFLAN VSHELRAPVT
AIIGLGRLLT DSGSDELTSE QARQVDLIRT SASDLLTLVN DLLDLAKAEA GRIEPNWSEV
DLKAMFGQLR GTLRPMVTRP EVELVVDEPT LPVLRSDEVL LAQVLRNLLT NALKFTETGS
VRLSVRPIDG DAEFVVADTG TGIPPELQER IFEEFYQVPG SKPVSGKGTG LGLPYARRLA
GILGGGLRVD SAPGEGSTFT LRLPITS
//
