ID A0A0A6YWB4_MOUSE Unreviewed; 66 AA.
AC A0A0A6YWB4;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Guanylate cyclase 1, soluble, alpha 1 {ECO:0000313|Ensembl:ENSMUSP00000141478.2};
DE Flags: Fragment;
GN Name=Gucy1a1 {ECO:0000313|Ensembl:ENSMUSP00000141478.2,
GN ECO:0000313|MGI:MGI:1926562};
GN Synonyms=Gucy1a3 {ECO:0000313|MGI:MGI:1926562};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141478.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141478.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141478.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000141478.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141478.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR ProteomicsDB; 359809; -.
DR Antibodypedia; 4394; 341 antibodies from 35 providers.
DR Ensembl; ENSMUST00000192289.2; ENSMUSP00000141478.2; ENSMUSG00000033910.14.
DR AGR; MGI:1926562; -.
DR MGI; MGI:1926562; Gucy1a1.
DR VEuPathDB; HostDB:ENSMUSG00000033910; -.
DR GeneTree; ENSGT00940000158285; -.
DR HOGENOM; CLU_2855606_0_0_1; -.
DR Proteomes; UP000000589; Chromosome 3.
DR Bgee; ENSMUSG00000033910; Expressed in olfactory tubercle and 276 other cell types or tissues.
DR ExpressionAtlas; A0A0A6YWB4; baseline and differential.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
PE 1: Evidence at protein level;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Proteomics identification {ECO:0007829|MaxQB:A0A0A6YWB4,
KW ECO:0007829|ProteomicsDB:A0A0A6YWB4};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 2..44
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|Pfam:PF00211"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000141478.2"
SQ SEQUENCE 66 AA; 7181 MW; DF5CE97AC22345E8 CRC64;
XAYCVAGGLH RESDTHAVQI ALMALKMMEL SNEVMSPHGE PIKVTQRLSW LCVHPEIKGG
ASTKLP
//
