GenomeNet

Database: UniProt
Entry: A0A0A8B3C1_9ACTN
LinkDB: A0A0A8B3C1_9ACTN
Original site: A0A0A8B3C1_9ACTN 
ID   A0A0A8B3C1_9ACTN        Unreviewed;       543 AA.
AC   A0A0A8B3C1;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   05-JUL-2017, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=JI75_00010 {ECO:0000313|EMBL:AJC11333.1};
OS   Coriobacteriaceae bacterium 68-1-3.
OC   Bacteria; Actinobacteria; Coriobacteriia; Coriobacteriales;
OC   Coriobacteriaceae.
OX   NCBI_TaxID=1531429 {ECO:0000313|EMBL:AJC11333.1, ECO:0000313|Proteomes:UP000031121};
RN   [1] {ECO:0000313|Proteomes:UP000031121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=68-1-3 {ECO:0000313|Proteomes:UP000031121};
RA   Looft T., Bayles D.O., Stanton T.B.;
RT   "Coriobacteriaceae sp. complete genome.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP009302; AJC11333.1; -; Genomic_DNA.
DR   RefSeq; WP_039687816.1; NZ_CP009302.1.
DR   EnsemblBacteria; AJC11333; AJC11333; JI75_00010.
DR   KEGG; cbac:JI75_00010; -.
DR   KO; K02313; -.
DR   Proteomes; UP000031121; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031121};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031121}.
FT   DOMAIN      226    350       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      450    519       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     234    241       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   543 AA;  60274 MW;  A94404262154DFCF CRC64;
     MDGEQLICEW GRICAKVVSY SGVDTAQVNA FFSRLQPQAM SEGFLMLTAD NEFIRNWVET
     HYVGLVKQAL VDLNGIEYAV LIEVDPSQSN PAGNMAAMPQ MASAPADADP SEEGASANQA
     PQTARAECEP PVQSGSGAAA SLNPAVMSAL EAARERAMRS AAAQMSAERV ETVAVPAPVE
     QTAPSAVVEK PRRSSAFTFE NYVIGDSNRV AYSMAVSVAE NPGGTRMNPL FIYGQSGLGK
     THLIRAIENY IEANMPHLEC VYVDAASFVN QYIDAGAEHD RNKQSYRNFQ NKYEQADVML
     LDDVQQLQGK KQTLDLFFQI MNNRIEKGYQ VILSADRAPS NIDMDQRYIS RFNSGGTFDI
     QPPEVETKLS IIRNFMRDYE DMNPESTASL SDEVQNYIAE NSSSNIRELK SAVTKVLASI
     EAFENDVIGI ADVRRLLEDH FSGGAMKKTT IEDIQKACEE YYRVSHADLV GPKRQRDISY
     ARKMCMYLSR EMLDIPFAQV GLAFGDRDHA TVMYAVNDVE SRFTKERAVQ EEVETIKKII
     RNI
//
DBGET integrated database retrieval system