ID A0A0A8EZM2_9ACTN Unreviewed; 866 AA.
AC A0A0A8EZM2;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Putative glycine betaine ABC transporter substrate-binding and permease component {ECO:0000313|EMBL:AJC59601.1};
GN ORFNames=GZL_07045 {ECO:0000313|EMBL:AJC59601.1};
OS Streptomyces sp. 769.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1262452 {ECO:0000313|EMBL:AJC59601.1, ECO:0000313|Proteomes:UP000031113};
RN [1] {ECO:0000313|EMBL:AJC59601.1, ECO:0000313|Proteomes:UP000031113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=769 {ECO:0000313|EMBL:AJC59601.1,
RC ECO:0000313|Proteomes:UP000031113};
RA Du Q., Wang Q., Li Q., Wang L., Zhang Z., Ren J., Wang J., Wang M.;
RT "Complete Genome Sequence of Streptomyces gongzhulingensis.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OsmX family.
CC {ECO:0000256|ARBA:ARBA00035642}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the binding-protein-
CC dependent transport system permease family.
CC {ECO:0000256|ARBA:ARBA00035652}.
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DR EMBL; CP003987; AJC59601.1; -; Genomic_DNA.
DR RefSeq; WP_039637890.1; NZ_CP003987.1.
DR AlphaFoldDB; A0A0A8EZM2; -.
DR KEGG; stre:GZL_07045; -.
DR HOGENOM; CLU_008673_0_1_11; -.
DR Proteomes; UP000031113; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd13639; PBP2_OpuAC_like; 2.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR007210; ABC_Gly_betaine_transp_sub-bd.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR47737; GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR PANTHER; PTHR47737:SF1; GLYCINE BETAINE_PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF04069; OpuAC; 2.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 49..78
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 90..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 134..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 201..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 239..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 302..321
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 87..266
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 866 AA; 94702 MW; AFE1A353341CE5A4 CRC64;
MPRIQIGSWA NDAVNWLRDN LDWLFNLVTT VLNGLYNAIH TVLAAPEPLI LAGILAVLAW
WLRGLPAAVL TFLGFALIDS IQQWNPTIES LSLVLVACLI TVVVAVPLGI WAARSKAVGG
VLRPVLDLMQ TMPAMVYLIP GILFFGLGVV PGIVATIVFS MPPAVRMTEL GIRQVDEELV
EAAEAFGTHP RRTLLRVQLP LALPTIMAGI NQVIMLALSM VVIAGMVGGG GLGASVYNAI
SSVNVALGAE AGLAVVILAM YLDRMTGALN QRVSPLGRRA LAKAQAALGG WKFLHWRPAT
SVAMVGVVVL ALLAGGMSFL GKSGDAASGG NGKPITLGYV NWDEGKATTY LWKEILEERG
YKPKVQALEA GPLFAGQARG DIDVQTNAWL PVTHAEYWNK YKDKLEDLGT WYDKTSLEIA
VPSYVKDVKT LDDLKGKAAE FGGKITGIEP GAGEMKILKD KVLKDYGLGG EYQVQESSTA
SMLSELDRAL HNKKPIAVTL WSPHWAYDKY PLTKLKDPKG SFGSGDGLHL IGRKGFSKDL
PEVAKWMKNF HLDEKQLTSL ENDIKSAGEG HEQDGVRTWL KKNPGLVEKI APSAHASYAK
GKDAGKAPHI GYPAWDEGIA TAYLWKNVLE KRGYRPDLRN LDVGPMWTGL STGQIDVETD
GWLPVAQKQY WDKYRNDLTD VGAWYDKTSL EIAVPSYVKD VKSMDDLRKH KDEFKGKIIG
IEPGTGEMQR LKSTVLPAYG LTDFEVTSAG TSAMLAELDR AYHKKEPIAV VLWSPHWAYS
KYQLTKLADP KGTWGANNQI KTLANKSFPD KFPEFHGWLK NWKMTPDELG SLEQDIQDAG
KGNEDKGVEK WIDDHPGIVD KMAPVK
//
