ID A0A0A8L2Y4_9SACH Unreviewed; 967 AA.
AC A0A0A8L2Y4;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=WGS project CCBQ000000000 data, contig 00099 {ECO:0000313|EMBL:CDO93220.1};
GN ORFNames=KLDO_g1522 {ECO:0000313|EMBL:CDO93220.1};
OS Kluyveromyces dobzhanskii CBS 2104.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=1427455 {ECO:0000313|EMBL:CDO93220.1, ECO:0000313|Proteomes:UP000031516};
RN [1] {ECO:0000313|EMBL:CDO93220.1, ECO:0000313|Proteomes:UP000031516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS2104 {ECO:0000313|Proteomes:UP000031516};
RA Nystedt B., Astrom S.;
RT "The genome of Kluyveromyces dobzhanskii.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO93220.1}.
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DR EMBL; CCBQ010000019; CDO93220.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A8L2Y4; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000031516; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF143; PHOSPHATE METABOLISM PROTEIN 7; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..625
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 673..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..164
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 187..380
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 391..664
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 868..960
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 766..818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..798
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 967 AA; 109219 MW; C629C7EC5E551636 CRC64;
MSSTGSESSS TSAFVSTLIV NGVIAAIFVW LFLTLRPKNK RVYQPRSLTD IKTIPESERT
EEVPPGYFNW IPFLLTKPHS YLIQHAGVDG YLFLRYLSIF AAISILGCFL LFPILLPVNA
TNGHNLEGFE LLAFSNVTNK NRFYAHVFLS WIFFGFIVFI IYRELYYYVT LRHSIQTTPL
YDGLLSSRTV ILTDLQGDFC SETQLNERFL NVSQVVLARN LSELQKLVED RTKTANKYES
TLNSVITKSV GMKIKADKKG ENVTEGTTNM DQPQDDLETY IPMKKRPKHR LSKIPILNIF
TSKKVDTLDY SVKHISELND KIRTDQDSWE DNETVGTAFV EFKSQYDAQR AYQSIPYLFD
KSAYDRALIG YGSDDINWQN TNLSRSARRS KRIGGNTILT LMIIFWAIPV AVVGCISNIN
FLTEKVPFLK FINNMPDVLM GIITGLLPTV LLALLMSLVP VFIKKVAVLS GALTRHESEL
YCHAWYYAFQ VVQVFLVVTL ASSASSTVTQ IIDDPSSAMS LLAENLPKAS NFYIAYFLLQ
GLAIPSGALL QAVPLILSKV LGRVLDKTPR QKWNRYNTLN APSWGVAYPV MELLVCIFIT
YSIISPIILV FSSLALGFFF IAYLYNLTYV MKFSYDLRGR NYPRALFQVF VGLYLAEVCL
IGLFVMAKTW GPVVLEAVFL AATALAHIYF KRRFIPLFDA VPLSAIEYSR GETDSYYPAK
DQGLKEIQVE GKKLADNILS EDKNGVFQET TKQDLQRVNM LPDDYEDSLE EESKSNNGNG
TISGSSKHNP NTFVGESEQF HKTKVPPEIP PQDVHQRERD PNAIVNEADA GLVLSDVKGY
PVNDPEEQLG LPSDIVKPKS IMARTKLFFQ PWVYYDFAIV RQTLPYVFND VVKYDLVYLE
TAFTDPCVTD KEPVIWCAKD PMGLSHQQIT IAAASDVDVR DDFTGYDEKG RTTFSNSPPD
YEMIAKK
//
