ID   A0A0A8L3J8_9SACH        Unreviewed;       362 AA.
AC   A0A0A8L3J8;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=Ribosomal RNA-processing protein 43 {ECO:0000256|ARBA:ARBA00030617};
GN   ORFNames=KLDO_g1122 {ECO:0000313|EMBL:CDO92813.1};
OS   Kluyveromyces dobzhanskii CBS 2104.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=1427455 {ECO:0000313|EMBL:CDO92813.1, ECO:0000313|Proteomes:UP000031516};
RN   [1] {ECO:0000313|EMBL:CDO92813.1, ECO:0000313|Proteomes:UP000031516}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS2104 {ECO:0000313|Proteomes:UP000031516};
RA   Nystedt B., Astrom S.;
RT   "The genome of Kluyveromyces dobzhanskii.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the RNase PH family.
CC       {ECO:0000256|ARBA:ARBA00006678}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDO92813.1}.
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DR   EMBL; CCBQ010000018; CDO92813.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A8L3J8; -.
DR   OrthoDB; 2045481at2759; -.
DR   Proteomes; UP000031516; Unassembled WGS sequence.
DR   GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IEA:UniProt.
DR   GO; GO:0000176; C:nuclear exosome (RNase complex); IEA:UniProt.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProt.
DR   GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IEA:UniProt.
DR   GO; GO:0016075; P:rRNA catabolic process; IEA:UniProt.
DR   CDD; cd11358; RNase_PH; 1.
DR   Gene3D; 3.30.230.70; GHMP Kinase, N-terminal domain; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   PANTHER; PTHR11097:SF9; EXOSOME COMPLEX COMPONENT RRP43; 1.
DR   PANTHER; PTHR11097; EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN; 1.
DR   Pfam; PF01138; RNase_PH; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          26..220
FT                   /note="Exoribonuclease phosphorolytic"
FT                   /evidence="ECO:0000259|Pfam:PF01138"
SQ   SEQUENCE   362 AA;  40399 MW;  96DAB234C360BC18 CRC64;
     MNTNTALQQD RHLSLETRPC SRGFEEFRDV LINDGNISRY SAKCQNANTN NVIGSSIVRS
     GKTFVITSIT GGIVEETLSA NNEDDVGEEE LITLSEGSNR LAKNASVHPV VEIQRGRVGG
     PTDEEMITSE RLHKTLLHSG ILKKTALRVL CGVRRTDENG KTTKIYSDEI LEEERKISES
     NNRRWSYVLY AKIQVFSRNG PIFDLCWNSL ISALKSVQLP RAFLDERAAD LKIAVRTRGR
     SMTIRETYDI LCDPEKSLPL QLNQHELGYG SNYGIIDIDP LAQLAKEENE MDVDKPTSVL
     LADIETEAEE SSIYSKLSLI TNKDGQFKSA TIIGGGSKIT PEMIKRCISL SKERSKDIES
     KI
//