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Database: UniProt
Entry: A0A0A8WLW0_9DELT
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ID   A0A0A8WLW0_9DELT        Unreviewed;       336 AA.
AC   A0A0A8WLW0;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:GAM08498.1};
GN   ORFNames=OR1_00770 {ECO:0000313|EMBL:GAM08498.1};
OS   Geobacter sp. OR-1.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=1266765 {ECO:0000313|EMBL:GAM08498.1, ECO:0000313|Proteomes:UP000030972};
RN   [1] {ECO:0000313|EMBL:GAM08498.1, ECO:0000313|Proteomes:UP000030972}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR-1 {ECO:0000313|EMBL:GAM08498.1,
RC   ECO:0000313|Proteomes:UP000030972};
RX   PubMed=23668621; DOI=10.1021/es400231x;
RA   Ohtsuka T., Yamaguchi N., Makino T., Sakurai K., Kimura K., Kudo K.,
RA   Homma E., Dong DT., Amachi S.;
RT   "Arsenic dissolution from Japanese paddy soil by a dissimilatory
RT   arsenate-reducing bacterium Geobacter sp. OR-1.";
RL   Environ. Sci. Technol. 47:6263-6271(2013).
RN   [2] {ECO:0000313|EMBL:GAM08498.1, ECO:0000313|Proteomes:UP000030972}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR-1 {ECO:0000313|EMBL:GAM08498.1,
RC   ECO:0000313|Proteomes:UP000030972};
RA   Ehara A., Suzuki H., Amachi S.;
RT   "Draft Genome Sequence of Geobacter sp. Strain OR-1, an Arsenate-
RT   Respiring Bacterium Isolated from Japanese Paddy Soil.";
RL   Genome Announc. 3:e01478-14(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAM08498.1}.
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DR   EMBL; BAZF01000003; GAM08498.1; -; Genomic_DNA.
DR   EnsemblBacteria; GAM08498; GAM08498; OR1_00770.
DR   Proteomes; UP000030972; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030972};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030972}.
FT   DOMAIN       33    161       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      244    313       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND      41     48       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   336 AA;  38162 MW;  02B655B4A9BBC03D CRC64;
     MNPKYTFEKF VCGSSNQFAY AASQAVANNP ATNYNPLFIY GGVGLGKTHL LIAIGNQILA
     TNKSARICYY TSEKFMNEMI NSLRHKKMDD FRNKFRKADV LLIDDIQFMA NKPATQEEFF
     HTFNSLYESH KQIVLTSDKF PKEIPELEER LRSRFEWGLI ADIQPPDTET KSAILKKKAE
     FDGILLPDDV ALFLSSSSAS NVRELEGMLV RLGAYSSLTN SKITLTMAKE VLKDIIVDKS
     KDISIEYIQK AVADHFQLKI SDLKSDKRIK TLVVPRQIAI FICRELTKAS YPEIGDKFGG
     KDHSTVIHSV KKIEKLLGQD HEIRNTIEII RRSLLT
//
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