ID A0A0B0MAA6_GOSAR Unreviewed; 976 AA.
AC A0A0B0MAA6;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DNA repair complementing XP-C cells {ECO:0000313|EMBL:KHF97241.1};
GN ORFNames=F383_15883 {ECO:0000313|EMBL:KHF97241.1};
OS Gossypium arboreum (Tree cotton) (Gossypium nanking).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29729 {ECO:0000313|EMBL:KHF97241.1, ECO:0000313|Proteomes:UP000032142};
RN [1] {ECO:0000313|Proteomes:UP000032142}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. AKA8401 {ECO:0000313|Proteomes:UP000032142};
RA Mudge J., Ramaraj T., Lindquist I.E., Bharti A.K., Sundararajan A.,
RA Cameron C.T., Woodward J.E., May G.D., Brubaker C., Broadhvest J.,
RA Wilkins T.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHF97241.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JRRC01000453; KHF97241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B0MAA6; -.
DR Proteomes; UP000032142; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000032142}.
FT DOMAIN 651..702
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 704..766
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 773..847
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 18..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 840..867
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 24..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..916
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 108564 MW; 56F5A3154B362F37 CRC64;
METKEEFLNI GTLARKSQEG VNKLLRRSSR LSSSGKKEQD GFSLENDPKT NEQEVVHTMD
VCNASTVEGC HRDAIENSQA KEQEVVHSMD VCNASMVEDC HREAIENSQA KEQEVVHSMD
AHNASPGDDC HKDTLLDDSE EMNDSDWEDG PILKPDPVDR SPNERMKGLT IEFDEPSGST
GGRKPVRRAS AEDKELAELV HKVHLLCLLA RGRLIDNACD DSLIQASLLS LLPTHLLKIS
EFTANALTPL VTWFHDNFHV RNLARAERSF RTALATALET HEGTPEEIAA LSVALFRALK
FTARFVSILD VASLKPEADK YEPSNQAAER VSGGIFSTST LMVDNLKRAS IAPSPFQTSP
CSEKDDYGKS SRKSKDGCSM SNIAQSRGST SVNESTDGKS TCQVQPDTSQ QCVPKNSQGL
KRKGDLEFEM QLAMAISATS VETHENIHDS SNGNNSLEGS IPTKRWKRIE RVESASCSQG
FSTALGSRKV GSPLFWAEVY CDGENLTGKW VHVDAVNAII DGEQKVEDAA AACKTSLRYV
VAFAGHGAKD VTRRYCMKWY KIAPKRVNST WWDSVLAPLR QLESGGTGGT IKVSEHPGEN
SSLNHVILPE KSGQEASKEY GSKIEVESSV KDSFIATRNS LEDMELETRA LTEPLPTNQQ
AYKNHALYAL ERWLTKYQIL HPKGPILGFC SGHPVYPRSC VQTLKTRERW LREGLQIKGT
ETPIKVLEQS SKLKKVRVSE DVCDEIDSKE TIELYGKWQL EPLLLPRAVN GIVPKNEHGQ
VDVWSEKCLP PGTVHLRLPR VFVVAKRLEI DYAPAMVGFE FRNGRAVPVY DGIVVCTEFK
DAILEAYAEE EERRAAVEKK RTEAQAISRW YQLLSSVITR QKLNSYYRDS SSSQPSGNIQ
DKNIETKTPV QSSKDSKQPT AHRKANNQDT THTTSLVALE VGHEHVFLTK NESFDPENSI
RTKRCECGFS IQVEEL
//
