ID A0A0B1PEH8_UNCNE Unreviewed; 1479 AA.
AC A0A0B1PEH8;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Putative ras gtpase activating protein {ECO:0000313|EMBL:KHJ35049.1};
GN ORFNames=EV44_g3976 {ECO:0000313|EMBL:KHJ35049.1};
OS Uncinula necator (Grape powdery mildew).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=52586 {ECO:0000313|EMBL:KHJ35049.1, ECO:0000313|Proteomes:UP000030854};
RN [1] {ECO:0000313|EMBL:KHJ35049.1, ECO:0000313|Proteomes:UP000030854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=c {ECO:0000313|Proteomes:UP000030854};
RX PubMed=25487071;
RA Jones L., Riaz S., Morales-Cruz A., Amrine K.C., McGuire B., Gubler W.D.,
RA Walker M.A., Cantu D.;
RT "Adaptive genomic structural variation in the grape powdery mildew
RT pathogen, Erysiphe necator.";
RL BMC Genomics 15:1081-1081(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHJ35049.1}.
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DR EMBL; JNVN01000556; KHJ35049.1; -; Genomic_DNA.
DR STRING; 52586.A0A0B1PEH8; -.
DR HOGENOM; CLU_000972_1_0_1; -.
DR OMA; RELMCPE; -.
DR OrthoDB; 12619at2759; -.
DR Proteomes; UP000030854; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:UniProt.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd21206; CH_IQGAP; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF14; PATTERNED EXPRESSION SITE; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50096; IQ; 4.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030854}.
FT DOMAIN 264..370
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 864..1096
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 105..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1479 AA; 172112 MW; 22B185B4CB87B072 CRC64;
MNDPLITHHL HPLRQTHNLD YSATTTRKSS SSSIQSSVFS NSASGFDRFH TSIHSPNSSL
GSSYRDSVSE TRDLSAMLNE NWNSSYDSLP IRTYNSMKHS AYSPLQNKTP SISNDMKINY
SPAQSEGLSE RPKKNSRTNS NLYKSESSIL SRANSICQRS SLLHSNSIHH LQSSIRAPDL
HSLQKSSTSQ LRTLSKFAKD ITSDYFNIFS PTQKVAGLYG RRKLQKSNTA KVNRSLPSNR
RLYEWKTRNW MDSERQFLQA YEYFCHISEA KEWIEKVLQR PIPPIVQLEE VLRDGVTLAE
IVVTLRPDKK IRIFRHPKLQ YRHSDNIATF FRFLADVELP DLFRFELTDL YEKKNTPKVI
YCIHALSWLL YRNNTVDFPI GNLLGQLEFE HHELEEMQKG LEKAGVSMPS FENMGADFGL
NSVPNSEFEQ IKSEEDLIRS KLEKNLPIII DLQAQAREAM NRLQLGEIMH QLWDSEETLI
YFQSIIRGDF ARQVINYRIS MRRFSTSLQS IVRGFLTRHR WAGQNFFWKE DEEKLITLQN
LIRSKTVRSK LDRVQLQLVK SKDNTSQFQA QIRGFLIQRS LTAQLNEAKI CLCSISYLQA
AIRGMSSRRI CAKNYQILSD ETISIKTIQA SARAVIVRRN LSDLKAQLRE ISPVYISIQS
ILRGNQSRQQ FQLSAAQASL IRLKFEEKLR YFMENMEKVV KIQSFVRSRL QGEAYKILTT
GKNPPVNTVK NFVHLLNDSD FDFNEEIEFE RLRKTVVQQV RQNEMAEQYI DQLDIKIALL
VKNKITLYEV VRHQKNFGGH PSNLLNTTMV SGSQFDLKAL NKSSRKKLES YQQLFFTLQT
QPHYLARLFK HIRQQGTAEI DCNRIETLMM VLFGYAQKRR EEYYLLKLMT RSAKEEVDSA
VSIKESLRGN FIWTRILANY TRSPRDRRFL RELLGPFIQA SIIGDPTLDL ESDPMQIYCS
VISNEELRTG QASHRPIDIT REQAIKDTET RELFINHLRD LREIVDDFLL SLESLVNKMP
YGIRFVCQQI FQAIFQRFSC ESQQLLLQTV GNWLWKIYLQ LAFLAPVITG IIERQMTPLL
KRILSEIAKV LNQISSGRLF GGENIYLQPL NAYMENAIER VTAIFANIIS VSDAESTFDI
DEFNDLYAKV KPTLYIKMDD IFAIHKLIEA DLPHICQNKD DLLRDIIHEL GSAKNNENEM
LGVSSIEILM KLNPKLHDIE DPEADIKELF METKRCVLYI IRVQTGSNLM EILIRPITPE
DEIKWNSVII EEFSVENRAR GAYSDINSLV DIKSMSYKDL KRTALENVLK LEQLGRISRQ
NFYQDILNAI ALDIRNKSRR RVQRHRELEG VRLTLANSNE EAEWLESQRK SYDNYIEQAM
ISLQKKGKNL FLMPFSKQYN HERELERSGR KPKFGSFKYS THTLFDKGVL VSWKGYTDRD
WDKTNILISR DEVEFFSLKA AKEVFKFLES VLKYLWNRY
//
