ID A0A0B1RTG4_OESDE Unreviewed; 407 AA.
AC A0A0B1RTG4;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059};
DE EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};
DE Flags: Fragment;
GN ORFNames=OESDEN_24422 {ECO:0000313|EMBL:KHJ75959.1};
OS Oesophagostomum dentatum (Nodular worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ75959.1, ECO:0000313|Proteomes:UP000053660};
RN [1] {ECO:0000313|EMBL:KHJ75959.1, ECO:0000313|Proteomes:UP000053660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ75959.1,
RC ECO:0000313|Proteomes:UP000053660};
RA Mitreva M.;
RT "Draft genome of the hookworm Oesophagostomum dentatum.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00000301,
CC ECO:0000256|RuleBase:RU362059};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167,
CC ECO:0000256|RuleBase:RU362059}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167, ECO:0000256|RuleBase:RU362059}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|RuleBase:RU003718}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN612232; KHJ75959.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1RTG4; -.
DR Proteomes; UP000053660; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF162; UDP-GLYCOSYLTRANSFERASE FAMILY 305 MEMBER A1, ISOFORM A-RELATED; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU003718};
KW Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003718}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KHJ75959.1"
SQ SEQUENCE 407 AA; 46652 MW; EFF9EDBC4A5F3510 CRC64;
LYQTLFIVEL DPDFKYSTGT QFVNHIIRYS SPYHNSADWR SLTFKRNEVF NSILGFNFID
LIKVQMYAYR VCKGILEDSG LIRLMHDSKF DLGVFEMFHH CPAGVMELAG IPKTMLVSAI
GIGYHHYRLL GMERQSSFVP ASFTMCGGRM TFLERLYNVF INGCGFVFSN IFEHFEQSLF
ERRFPGFKVL HDLVKDKTDF MLMNSNEFTE STRPTLRSIQ YVGGATIPEP EPLDEDFDWI
LSRGSKGAIL FSLGSLVKPS NMPLAFREGA FIFIDTFVDA FRAFPDYSVL WKDDIEMNFT
YPNIHFREWV PQVDLLADGR VKLFITHCGM NSMQESLLFG VPMVTIPLFA DQDSNAAVAA
ERGYSVNLNK LSITTEKIID AISAVLGKPG EERYRITSYF LRLIQYV
//
