ID A0A0B1SK51_OESDE Unreviewed; 610 AA.
AC A0A0B1SK51;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:KHJ85683.1};
DE Flags: Fragment;
GN ORFNames=OESDEN_14585 {ECO:0000313|EMBL:KHJ85683.1};
OS Oesophagostomum dentatum (Nodular worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ85683.1, ECO:0000313|Proteomes:UP000053660};
RN [1] {ECO:0000313|EMBL:KHJ85683.1, ECO:0000313|Proteomes:UP000053660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ85683.1,
RC ECO:0000313|Proteomes:UP000053660};
RA Mitreva M.;
RT "Draft genome of the hookworm Oesophagostomum dentatum.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN562977; KHJ85683.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1SK51; -.
DR Proteomes; UP000053660; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:KHJ85683.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:KHJ85683.1};
KW Transferase {ECO:0000313|EMBL:KHJ85683.1}.
FT DOMAIN 406..584
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 204..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 610
FT /evidence="ECO:0000313|EMBL:KHJ85683.1"
SQ SEQUENCE 610 AA; 69814 MW; 7F2C50ACB284954E CRC64;
MARANEDPQL ARILEAMVEQ MRLHHEEMKS LLAALASSQK PAVQDVSIDQ YDQLSKDVQK
FVPDDETGNT FDYCFKRYGP LIRDSTLPDG KKRDSVLMKL DEEAYRKYAD DILPLHPHEV
EFETTVTNLQ KLFASKKTLI RRRYECLRIV YPLLTSSHVP FPLKMDSTDM EQCQDIHAVQ
KKKVKCYNCG GPHYRSTCPL LSSNTGQEMR QKKSRRKRSH RREKNQCKNV VIFAVENART
YLDVKIGGRF LHFLFDTGTD ITLISRRTWK RFGSPTLEPC ATPVKTADGS PMKIDGRFAT
DFSVKDRITG EMIQGKGLCY VTESTKIRVE KYHCRMVAQG ESQRAEVIAD LEKQFAEVFK
CELERCTKTK AKLMLKDNAT AVFKKKRPVP YASVPDLDEE IDRLVAEGVI SPVDHSEWAA
PIVVVMKKNG KIRLCADFST GLNDALQLHQ HPLPTAEDVF TKLNGGQLFT QIDFAEAYVQ
VEVDEESKEM LTINTPRGLF RYNRLPFGVK SAPGMFQQIM DAMICGLEGV AAYLDDVIVT
GRTDAEHRQN LEALFRRIQE YGFHVRMEKC NFLMPQIRYL GCIIDKDGRH PDPEKIKVIR
QMPVPKNVQE
//
