ID A0A0B1TCV8_OESDE Unreviewed; 672 AA.
AC A0A0B1TCV8;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Glycosyltransferase family 28 protein {ECO:0000313|EMBL:KHJ93637.1};
GN ORFNames=OESDEN_06446 {ECO:0000313|EMBL:KHJ93637.1};
OS Oesophagostomum dentatum (Nodular worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ93637.1, ECO:0000313|Proteomes:UP000053660};
RN [1] {ECO:0000313|EMBL:KHJ93637.1, ECO:0000313|Proteomes:UP000053660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ93637.1,
RC ECO:0000313|Proteomes:UP000053660};
RA Mitreva M.;
RT "Draft genome of the hookworm Oesophagostomum dentatum.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00000301};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995}.
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DR EMBL; KN550675; KHJ93637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1TCV8; -.
DR Proteomes; UP000053660; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF23; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF00201; UDPGT; 2.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 2.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KHJ93637.1}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..672
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002065845"
SQ SEQUENCE 672 AA; 74883 MW; 12715AA6CF37C7AC CRC64;
MLLLPALSIL ITCCSSYKIL VYNRKSAYSH MNFLGKVADT LVDAGHDVVT LQPVIVPMGA
NGTRKSRIIH VELDKKLAAD LMGDRKDNAK MWTNNAANPL LVLEHIPFMR GLTIATTKRI
LDDKELLEQL KSENFDVGIA ELFDYGGIPV FEAIGLKNII GAHTLSCLSE ATAYAIGVPV
IPSFMPASQG ITDDSTSFSN RAINLLFTYF SYYFQISIAD AAETVMMEKL GKAAVPVWDV
VANMSWILTN TEPFLEFAKP TLHKVVDIGG IGVPKPKPLE EKWNKILNLR SRTVLISFGS
MVKSKAMPYE YKTAIIELVK SYPDITFIWK YEDPDDAPFA AGVENLFLSQ WTPQNDLLAS
QGITDDSTSF SNRAINLLFT YFSYYFQVSI ADAAETVMME KLGKAAVPIW DVVANMSWIL
TNTEPFLEFA KPTLHKVVDI GGIGVPKPKP LEEKWNKILN LRSRTVLISF GSMVKSKAMP
YEYKTAIVEL VKSYPDITFI WKYEDPDDAP FAAGVENLFL SQWTPQNDLL ADDRLTLFIT
HGGAGSLLES ATSGKPVILI PLYGDQVRNA KLAIRHGFGI MLTKEDLGDS TLMHETVAKI
LNDKKYTKAA HRIRNLLAKR PFSPEEKLLK TVELAVEFGP IPELYILDTG CYMFFCYLLG
VPLLKDDFKG CI
//
