ID A0A0B1TL75_OESDE Unreviewed; 1977 AA.
AC A0A0B1TL75;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Myosin head {ECO:0000313|EMBL:KHJ98009.1};
GN ORFNames=OESDEN_02007 {ECO:0000313|EMBL:KHJ98009.1};
OS Oesophagostomum dentatum (Nodular worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ98009.1, ECO:0000313|Proteomes:UP000053660};
RN [1] {ECO:0000313|EMBL:KHJ98009.1, ECO:0000313|Proteomes:UP000053660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ98009.1,
RC ECO:0000313|Proteomes:UP000053660};
RA Mitreva M.;
RT "Draft genome of the hookworm Oesophagostomum dentatum.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril
CC {ECO:0000256|ARBA:ARBA00004657}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KN549368; KHJ98009.1; -; Genomic_DNA.
DR Proteomes; UP000053660; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 3.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF7; MYOSIN-3; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 31..80
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 84..810
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 685..707
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1042..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1951..1977
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1180..1763
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1798..1938
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1955..1977
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 180..187
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1977 AA; 226445 MW; FA12F15C5BBADAFE CRC64;
MSNTDFEKDP GFVYLGMSRE ARAESASRPF DSKKNVWIPD AEEGFIAAEI QSVQGEQVTV
VTAKGNTVTV KKDQAQEMNP PKFDKTEDMA NLTFLNEASV LANLKDRYKD MMIYTYSGLF
CVVINPYKRL PIYTESVIKF YMGKRRNEMP PHLFAVSDEA YRNMVQGKQC TTNQSMLITG
ESGAGKTENT KKVISYFAIV GATQSAKQEG TKGVSSKEGS KGGTLEEQIV QTNPVLEAFG
NAKTVRNNNS SRFGKFIRTH FSAQGKLAGG DIEHYLLEKS RVVRQAPGER SYHIFYQIMS
GHDPKLRDFL KLNHELRYYH FCSQAELTID GVDDKEEMGL TQEAFDIMGF EDEEVSDMYK
SCAAIMHMGE MKFKQRPREE QAEPDGDEGL PLYSAYTNCK HGVLVTDAQN VAHCLGINAE
ELLKALTKPR VRVGTEWVNK GQNLEQVHWA VAGLGKAIYA RICNKTLDAK QIERRYFIGV
LDIAGFEIFD FNSFEQLWIN FVNERLQQFF NHHMFVLEQE EYKREGIQWT FIDFGLDLQA
CIELIEKPLG LISMLDEECI VPKATDMTYV QKLNDQHLGK HPNFQKPKPP KGKQSEAHFA
VVHYAGTVRY NATNFLEKNK DPLNDTAVAL LKTHSQGCKL MLEIWADYQT QEEAAEAAKS
GAGGGKKKGK SASFMTVSMI YRESLNNLMN MLYQTHPHFI RCIIPNEKKT SGLIDSALVL
NQLTCNGVLE GIRICRKGFP NRMLYDDFKH RYACLAAEKA KSSDDVKVAS IAITDALVTE
GHLKDEEFKI GNTKVFFKAG ILARLEDRRD EILKVIMTNF QSRVRWYLGL TDLRRRMQQQ
AGLLILQRNV RSWCTLRTWE WFKLYGKVKP LLKAGKEHEE MEKLSDKIKA LEEAVAKGDE
SRKQLESQVA GLVEEKNQLF LNLEKEKANL QDAEERNQKL AALKADLDKQ LAEVQYEQEI
AEHKKHAQDL ELSLKKAESE KQARDHNIRS LQDEMANQDE AVARLNKEKK HQEEVNRKLM
EDLQAEEDRV NHMEKVRAKL EQQLDDLEDS MDREKRSRQD LEKAKRKVEG ELKVAQENID
EITKQKHDVE QNLKKKETEL HQLSTRLEEE QSLVAKLQRQ IKELQARIAE LEEELENERQ
SRAKASLART GSNLLQRELE EISERLEEQG GATAAQLEAN KKREAELAKL RRDQEESNLN
HETALASLKK KHHDAVAELT DQLEQLQKLK AKTDKEKAQL QRELEELSAS VDSEVRSRQD
IEKQLKVVEV QYAEAQTKAD EQSRQLNDFA ALKNRLHNEN GDLGRQLEDM ENQLNSLHRL
KAQLTSQLEE TKRSYDEEAR ERQALAAQVK NFEHENDSLR EQLDTESEAK AELLRQISKQ
NAEIQQWKAR FESEGLTKLD EIEEAKRKLQ GKVQELTDAN EMAFAKIGSL EKTRHKLMQD
LDDAQVDVER AASYAAALEK KQKGFDKIID EWRKKHDDLA AELDAAQRDN RNLSTDLFRA
KTAQDELTEH LESVRRENKQ LAQEVKDLAD QLGEGGRSVH ELQKMVRRLE VEKEELQKAL
DEAEAALEAE EAKVLRAQVE VSQIRSEIEK RIQEKEEEFE NTRKNHQRAL ESMQATLEAE
TKHKEEALRI KKKLEADINE LEIALDHANR ANADAQKTIK KYMETVRELQ LQVEDEQRQK
DEIREQFLNS EKRNAILQTE KEELTQVAEA AERARRNAET DCIELREHNN DLSSQLNGIT
AVKRKLEGEL QAMHAELDET LAELNVDEMG KKAAADAARL AEELRQEQEH SMHVERIRKG
LEVQIKEMQI RLDEAEAAAL KGGKKIIAQL ESRIRGLEQE LDGEQRRHQE TDKNWRKSER
RVKEVEFQLE EDKKNQERLT ELIDKLQAKL KVFKRQVEEA EEVAATNLGK YRQLQAQLDD
AEERADVAEN ALSKMRNKIR ASASMVPTGS GGLGAGLAQS ASSAVVRSTS FARSQDF
//
