ID A0A0B1TQC3_OESDE Unreviewed; 837 AA.
AC A0A0B1TQC3;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Coatomer subunit beta {ECO:0000256|ARBA:ARBA00017024, ECO:0000256|PIRNR:PIRNR005727};
DE AltName: Full=Beta-coat protein {ECO:0000256|ARBA:ARBA00030841, ECO:0000256|PIRNR:PIRNR005727};
GN ORFNames=OESDEN_01986 {ECO:0000313|EMBL:KHJ98022.1};
OS Oesophagostomum dentatum (Nodular worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ98022.1, ECO:0000313|Proteomes:UP000053660};
RN [1] {ECO:0000313|EMBL:KHJ98022.1, ECO:0000313|Proteomes:UP000053660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ98022.1,
RC ECO:0000313|Proteomes:UP000053660};
RA Mitreva M.;
RT "Draft genome of the hookworm Oesophagostomum dentatum.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBUNIT: Oligomeric complex that consists of at least the alpha, beta,
CC beta', gamma, delta, epsilon and zeta subunits.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005727}. Golgi
CC apparatus membrane {ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane
CC protein {ECO:0000256|PIRNR:PIRNR005727}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR005727}. Cytoplasmic vesicle, COPI-coated
CC vesicle membrane {ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane
CC protein {ECO:0000256|PIRNR:PIRNR005727}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR005727}.
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DR EMBL; KN549366; KHJ98022.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1TQC3; -.
DR Proteomes; UP000053660; Unassembled WGS sequence.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR011710; Coatomer_bsu_C.
DR InterPro; IPR016460; COPB1.
DR PANTHER; PTHR10635; COATOMER SUBUNIT BETA; 1.
DR PANTHER; PTHR10635:SF0; COATOMER SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF07718; Coatamer_beta_C; 1.
DR PIRSF; PIRSF005727; Coatomer_beta_subunit; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR005727};
KW Cytoplasmic vesicle {ECO:0000256|PIRNR:PIRNR005727};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005727};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005727};
KW Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW Transport {ECO:0000256|PIRNR:PIRNR005727}.
FT DOMAIN 23..530
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT DOMAIN 681..803
FT /note="Coatomer beta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07718"
SQ SEQUENCE 837 AA; 93521 MW; F11A061668AEA227 CRC64;
MSSGELPCYT LIHVPTDADL PNEAQLKEKF EKGTDKEKTE ALKKLIYMIQ NGEKIGQGML
MYVIRFLLPS SDHTLKKTLL IFWEVVPKTN AQGKLLQEMI LVCDAYRKDL QHPNEFVRGS
TLRFLCKLKE PELLEPLMPS IIGCLEHRHS YVRRNAVCAI FTIYRNFEFL IPDAPELVSN
FLEGEQDASC KRNAFMMLLH VDQARALDYL SGCIDQVAQF GDILQLIIVE LIYKVCHANP
AERSRFIRCV YNLLQSSSAA VRYEAAGTLV TLSAAPAAIK AAAQAYIDLI VKESDNNVKL
IVLDRLMDLR QTPSHEKVLQ ELVMDILRVL SSPGLDVRQK TLNLALDLVS SRNVGDMVMF
LKKEIAKSTS EPAEEAGRYR QALVKTLHSA TIKFPDVAPS IVPVLMEFLS DENEVAAQYV
LLFVREAVHK LPHLKETILH SLQEGLPTIR KPKVFMAALW ILGTYCENDA AVLSVLRLIK
NSLGELPIVE SEMRQMEGEE TPQEESTEKK ATAKQLVTAD GTYATQSALS ATTKTVAKEK
PPLRHVSCKR RFCLILLILQ FLLDGDFFLG ASLATVLNKL AEQFTKNNGA GSQRANRFRG
ECMFILASII NLGKSGLAKQ NITEDDLDRM GTTIKLLAQG CSEFDDIFVE KCKDSLELML
ASRHQDKTDE FSMKKKNIVE VDKTIMFTQL SARADASIGE NLFDLSLSQA LGTAPKTQKF
DFSSSKLGKV IQLAGFSDPV YAEAYVSVNQ YDIVLDVLIV NQTADTLQNV SLELSTVGDL
KLVDKPTPIT LAPADFANIK VILLLVSFSV YGSFIMNSLN DYAHRKFWAF LLTINYC
//
