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Database: UniProt
Entry: A0A0B2K0J5_9FIRM
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ID   A0A0B2K0J5_9FIRM        Unreviewed;        73 AA.
AC   A0A0B2K0J5;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Translational regulator CsrA {ECO:0000256|HAMAP-Rule:MF_00167};
GN   Name=csrA {ECO:0000256|HAMAP-Rule:MF_00167};
GN   ORFNames=NZ47_09015 {ECO:0000313|EMBL:KHM51702.1};
OS   Anaerovibrio lipolyticus.
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC   Anaerovibrio.
OX   NCBI_TaxID=82374 {ECO:0000313|EMBL:KHM51702.1, ECO:0000313|Proteomes:UP000030993};
RN   [1] {ECO:0000313|EMBL:KHM51702.1, ECO:0000313|Proteomes:UP000030993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5S {ECO:0000313|EMBL:KHM51702.1,
RC   ECO:0000313|Proteomes:UP000030993};
RX   PubMed=23950883;
RA   Prive F., Kaderbhai N.N., Girdwood S., Worgan H.J., Pinloche E.,
RA   Scollan N.D., Huws S.A., Newbold C.J.;
RT   "Identification and characterization of three novel lipases belonging to
RT   families II and V from Anaerovibrio lipolyticus 5ST.";
RL   PLoS ONE 8:E69076-E69076(2013).
CC   -!- FUNCTION: A translational regulator that binds mRNA to regulate
CC       translation initiation and/or mRNA stability. Usually binds in the 5'-
CC       UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding,
CC       thus repressing translation. Its main target seems to be the major
CC       flagellin gene, while its function is anatagonized by FliW.
CC       {ECO:0000256|HAMAP-Rule:MF_00167}.
CC   -!- SUBUNIT: Homodimer; the beta-strands of each monomer intercalate to
CC       form a hydrophobic core, while the alpha-helices form wings that extend
CC       away from the core. {ECO:0000256|HAMAP-Rule:MF_00167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00167}.
CC   -!- SIMILARITY: Belongs to the CsrA/RsmA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHM51702.1}.
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DR   EMBL; JSCE01000177; KHM51702.1; -; Genomic_DNA.
DR   RefSeq; WP_039209486.1; NZ_JSCE01000177.1.
DR   AlphaFoldDB; A0A0B2K0J5; -.
DR   STRING; 82374.NZ47_09015; -.
DR   eggNOG; COG1551; Bacteria.
DR   Proteomes; UP000030993; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:InterPro.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:1902208; P:regulation of bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0006109; P:regulation of carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.4380; Translational regulator CsrA; 1.
DR   HAMAP; MF_00167; CsrA; 1.
DR   InterPro; IPR003751; CsrA.
DR   InterPro; IPR036107; CsrA_sf.
DR   NCBIfam; TIGR00202; csrA; 1.
DR   PANTHER; PTHR34984; CARBON STORAGE REGULATOR; 1.
DR   PANTHER; PTHR34984:SF1; CARBON STORAGE REGULATOR; 1.
DR   Pfam; PF02599; CsrA; 1.
DR   SUPFAM; SSF117130; CsrA-like; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis {ECO:0000256|HAMAP-Rule:MF_00167};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00167};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030993};
KW   Repressor {ECO:0000256|HAMAP-Rule:MF_00167};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW   Rule:MF_00167};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845, ECO:0000256|HAMAP-
KW   Rule:MF_00167}.
SQ   SEQUENCE   73 AA;  8180 MW;  BB98812B1D9413B1 CRC64;
     MLVLTRHPKQ QIMIGDDIVI NIVEVNGDNV RLAIDAPRSV KVYRGEIYKV IKDENRKAAA
     PVDNIDLSQA LPK
//
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