ID A0A0B2PKW1_GLYSO Unreviewed; 1099 AA.
AC A0A0B2PKW1;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982};
DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982};
GN ORFNames=glysoja_040821 {ECO:0000313|EMBL:KHN08364.1};
OS Glycine soja (Wild soybean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3848 {ECO:0000313|EMBL:KHN08364.1};
RN [1] {ECO:0000313|EMBL:KHN08364.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Root {ECO:0000313|EMBL:KHN08364.1};
RA Lam H.-M., Qi X., Li M.-W., Liu X., Xie M., Ni M., Xu X.;
RT "Identification of a novel salt tolerance gene in wild soybean by whole-
RT genome sequencing.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide;
CC Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16302;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
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DR EMBL; KN665951; KHN08364.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2PKW1; -.
DR Proteomes; UP000053555; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR045344; C-JID.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF259; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF20160; C-JID; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 19..185
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1099 AA; 125833 MW; 3854C9041BAA532C CRC64;
MASTSNAIFQ CTSSSSSSFE YDVFVSFRGE DTRNSFTAFL FEALKKQGIE AFKDDKDIRK
GESIAPELIR AIEGSHVFLV VFSKDYASST WCLRELAHIW NCFQPSTRHL LPIFYDVDPS
QVRKQSGDYE KAFAQHQQSS RFQDKEIKTW REVLNHVASL SGWDIRNKQQ HAVIEEIVQQ
IKNILGCKFS ILPYDNLVGM ESHFAKLSKL ICLGPVNDVR VVGITGMGGI GKSTLGRALY
ERISYRFNSS CYIDDISKLY GLEGPLGVQK QLLSQSLKER NLEICNVSDG TILAWNRLAN
ANALIVLDNV DQDKQLDMFT GSRNDLLRKR LGKGSIIIII SRDQQILKAH GVDVIYQVKP
LNDNDALRLF CKKVFKNNYI MSDFEKLTYD VLSHCKGHPL AIEVVGSSLF DKDVLHWRSA
LTWLRENKSK SIMNVLRISF DQLEDTHKEI FLDIACFFNN DMVEYVKEVL DFRGFNPESG
LLVLVDKSLI TMDSRVIRMH DLLCDLGKYI VREKSPRKPW KWSRLWDVKD FLKVKSDNKA
AENVEAIVLS KKSVILQTMR IDALSTMSSL KLLKFGYKNV GFQINFSGTL AKLSNELGYL
SWIKYPFECL PPSFEPDKLV ELRLPYSNIK QLWEGTKPLP NLRRLDLFGS KNLIKMPYIE
DALYLESLNL EGCIQLEEIG LSIVLSPKLT SLNLRNCKSL IKLPRFGEDL ILGKLVLEGC
RKLRHIDPSI GLLKKLRRLN LNNCKNLVSL PNSILGLNSL QYLNLSGCSK VYNTELLYEL
RDAEQLKKID KDGAPIHFQS TSSDSRQHKK SVSCLMPSSP IFQCMRELDL SFCNLVEIPD
AIGIMSCLER LDLSGNNFAT LPNLKKLSKL VCLKLQHCKQ LKSLPELPSR IEIPTPAGYF
GNKAGLYIFN CPKLVDRERC TNMAFSWMMQ LCSQVRLFSL WYYHFGGVTP GSEIPRWFNN
EHEGNCVSLD ASPVMHDHNW IGVAFCAIFV VPHETLLAMG FSNSKGPRHL FGDIRVDFYG
DVDLELVLDK SDHMCLFFLK RHDIIADFHL KHRYLGRWVS RYDGVLKESY AEVKKYGYRW
VYKGDIEQRK RKFGEIEEK
//
