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Database: UniProt
Entry: A0A0B2UP45_TOXCA
LinkDB: A0A0B2UP45_TOXCA
Original site: A0A0B2UP45_TOXCA 
ID   A0A0B2UP45_TOXCA        Unreviewed;      2067 AA.
AC   A0A0B2UP45;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   12-APR-2017, entry version 14.
DE   SubName: Full=Voltage-dependent T-type calcium channel subunit alpha-1H {ECO:0000313|EMBL:KHN70872.1};
GN   Name=Cacna1h {ECO:0000313|EMBL:KHN70872.1};
GN   ORFNames=Tcan_17342 {ECO:0000313|EMBL:KHN70872.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Ascaridida;
OC   Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN70872.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN70872.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN70872.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J.,
RA   Yang Y., Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W.,
RA   Jex A.R., Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KHN70872.1}.
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DR   EMBL; JPKZ01022848; KHN70872.1; -; Genomic_DNA.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR005445; VDCC_T_a1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR01629; TVDCCALPHA1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031036};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    151    170       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    194    213       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    286    309       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    407    425       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    445    471       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    751    771       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    839    860       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    917    943       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1230   1248       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1268   1289       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1301   1320       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1366   1388       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1469   1492       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1560   1581       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1593   1611       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1623   1641       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1690   1709       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1778   1803       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      149    477       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      719    950       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1229   1501       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1559   1814       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      940    979       {ECO:0000256|SAM:Coils}.
FT   COILED     1163   1195       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2067 AA;  235272 MW;  F630091F5CDDC3AD CRC64;
     MLQQPVAREL RSFQSLSRFS GPRGILNRRQ STLNARRLSH SRRKNTEAIV DDSQASSATG
     ACTSGDYVRA HLPRSKAVSL SLEASPMHPW YGSGQPSEQQ RQPQVEWHDE ADFVEDECDL
     PYPGFVEPAL HCLKQASPPR SWALRMVMNP WFDRLTMIVI LINCITLGMY RPCEDGGECA
     TYRCYVLSLI DHTIFAYFAL EMIIKIIALG FYGPAAYLSD TWNRLDFFIV CAGCAEYLLQ
     EYLGNINLTA IRTIRVLRPL RAVNRIPSMR ILVNLLLDTL PMLGNVLLLC FFVFFIFGIV
     GVQLWAGLLR NRCVINLPKT NMAINVTDVS LTRYYIPEDT SLEYICSQSD SSGLHTCNKL
     PPYTHNGVKC NLTLLEWEKV SNESCINWNI YYNECTVMHR NPFQGSVSFD NIGFAWVAIF
     LVISLEGWTD IMYYVQDAHS FWNWIYFVLL IVVGAFFMIN LCLVVIATQF AETKRRETER
     MIQERKRLRS SGSLSGSEQG ATSSKDGGSG DSVYAAIVRF ISQQSRRLKR RLIKEFRALR
     VRFFSKQASD SSNKTATVMN AVEAGSRPEG TGIQKGDQEH TEENTVSQQR RQGSRSTKRT
     RRRSSAASRK NKSNGSVQRV DGEVAADSFV KTPLARHGSS LSSDLSSGEE SDVEDADKWS
     ASEARMSGTN VRQNHRRSIA YNDNVQDVSL ISNGAKKSRI RWLRERIQAF VICNHFKRGI
     LFAILINTLS MGVEYHQQPE LLTTILEYSN YFFTGLFALE MLLKIIADGL FGYLSDGFNL
     FDGGIVALSV LELFQEGKGG LSVLRTFRLL RILKLVRFMP ALRYQLVVML RTMDNVTVFF
     GLLVLFIFIF SILGMNLFGC KFCKIEDNPF GGHVKKCERK NFDSLLWALI TVFQILTQED
     WNMVLFNGMA QTTPWAALYF VALMTFGNYV LFNLLVAILV EGFQESKEEE KRQLEEEARK
     KANEEEEERK RELELLLAKT SSPSFILNRK SDIKQCSCGH GQPNQLGLYE ARFPSFPFAS
     NNIPNFREVA GSSPKLRDGR TEAKEESKMD SDLLYDQIAT SGRIHSSMTG ADGGSQNLGA
     RSIRFNANDD GSDSDTDDEK RALRNKYRLN RHTSLVLPRL HTNYDMYGRG ARQRMNSWCG
     LHAMFNPYCP VHGRQALIEA YARDKFIQAS QELQKAIAEE ERREEERQNS AWRRLFRKTC
     MYRRADYSLY IFSPKNGIRI TCLQLTQKKW FDYTILFFIG INCITLAMER PSIPPKSVER
     QFLTLSGYVF TVIFTIEMTL KVVANGCLIG PGAYFKDGWN ILDGTLVIIS LVNVGFELLV
     HGDSPKIFGV IRVLRLLRAL RPLRVINRAP GVKLVVMTLI SSLKPIGNIV LICCTFFIIF
     GILGVQLFKG MMYHCIGHDI SNVTTKAECL QDPRNKWVNH RYNFDNLGQA LMSLFVLSSK
     DGWVSIMYQG IDATGVDMQP IENYNEWRMI YFISFLLLVG FFVLNMFVGV VVENFHKCKE
     ALEAEMRERA RQKRLERKLK RQQFEDQFGH KRKKKEKSHP YWYNYGQTRM FLNSVVTSKY
     FDLAIAAVIG INVISMAMEF YMMPAGLKYV LKALNYFFTA VFTLEAGMKL IALGIKRFFK
     ERWNQLDMFI VVLSIAGIIF EEFEALELPI NPTIIRVMRV LRIARVLKLL KMAKGIRSLL
     DTVGEALPQV GNLGSLFFLL FFIFAALGVE LFGKLECSED HPCDGLGEHA HFKNFGMAFL
     TLFRIATGDN WNGIMKDALR DDCDPSDHCE SNCCVDPILA PCFFIIFVLI SQFVLVNVVV
     AVLMKHLEES NKREESAEAT NAMTGTDTDV NKTDTDIEDN LDSSSRKDPN EYDLAAELRE
     VEEKLAAEAQ HLRVSLIDSD EHHIENTCRM HPFFYDVNPT EQTLASEKNG MESNENRLIG
     HRTDLSSPPE SPSNCQNVID SSINQQIRAA SRMRCSLRSP YTINTQRWER SHSESCDSFG
     RRTLKADELR VHLNDDRYHS LVGIPTLECD ESAEEDATRL PEEGIIQKPR MHSRSFGGVD
     RNKEPKRDRS LAANAFSGES EGTHPEP
//
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