ID   A0A0B2USF6_TOXCA        Unreviewed;       297 AA.
AC   A0A0B2USF6;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Acetyl-CoA acetyltransferase A, mitochondrial {ECO:0000313|EMBL:KHN73951.1};
GN   Name=acat1-a {ECO:0000313|EMBL:KHN73951.1};
GN   ORFNames=Tcan_10833 {ECO:0000313|EMBL:KHN73951.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN73951.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN73951.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN73951.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC       {ECO:0000256|ARBA:ARBA00010982}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN73951.1}.
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DR   EMBL; JPKZ01002986; KHN73951.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2USF6; -.
DR   STRING; 6265.A0A0B2USF6; -.
DR   OMA; REHGLDH; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR   InterPro; IPR020616; Thiolase_N.
DR   PANTHER; PTHR18919:SF156; ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
DR   PROSITE; PS00098; THIOLASE_1; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Potassium {ECO:0000256|ARBA:ARBA00022958};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Transferase {ECO:0000313|EMBL:KHN73951.1}.
FT   DOMAIN          30..260
FT                   /note="Thiolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00108"
SQ   SEQUENCE   297 AA;  31296 MW;  B368D8B18EE51126 CRC64;
     MAATSRLVCN NLSKRAFTLS SRSASQFTDV VFVGAARTPV GSFRSSLATV PATTLGSAAI
     KGAIEHAKIK PSQVQEVFFG CVVPSDVGQG PARQAALGAG CDPTTIVTTL NKLCASGMKS
     IACGASILQL GLQEIVVGGG MESMSRAPFY IPRGDTPYGG LTVVDGLLRD GLMDAYSNKL
     MGYCADMVAK KFGITREEQD KFAIESYKKS AAAWEAGAWQ PEIVPIEVTK GKKTFTVDRD
     EEYTRVNFEK LPKLKPAFIK GARIVVHLIH ALKPGQKGCA AICNGGGGAG GMIIEKL
//