ID   A0A0B2UY06_TOXCA        Unreviewed;       708 AA.
AC   A0A0B2UY06;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Negative elongation factor C/D {ECO:0000313|EMBL:KHN73725.1};
GN   Name=NELFCD {ECO:0000313|EMBL:KHN73725.1};
GN   ORFNames=Tcan_17706 {ECO:0000313|EMBL:KHN73725.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN73725.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN73725.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN73725.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NELF-D family.
CC       {ECO:0000256|ARBA:ARBA00005726}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN73725.1}.
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DR   EMBL; JPKZ01003063; KHN73725.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2UY06; -.
DR   STRING; 6265.A0A0B2UY06; -.
DR   OMA; ARINPDH; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   InterPro; IPR006942; TH1.
DR   PANTHER; PTHR12144:SF0; NEGATIVE ELONGATION FACTOR C_D; 1.
DR   PANTHER; PTHR12144; NEGATIVE ELONGATION FACTOR D; 1.
DR   Pfam; PF04858; TH1; 2.
PE   3: Inferred from homology;
KW   Elongation factor {ECO:0000313|EMBL:KHN73725.1};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Protein biosynthesis {ECO:0000313|EMBL:KHN73725.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   708 AA;  80878 MW;  7FD15DBDF24B4D93 CRC64;
     MGRTSCMASG APETPMEEEL AVNGERNHDE QMECEENSAE NSKRFIREQC LQLLKSENEL
     QSLLAIYKPW VGTLPILDDL YDFLTSNDWN FARFLRKQKF VVPDFVMEPQ VFDVLGTFFK
     CGGEPDVVID SLSDNYASLG QICNVLGDML EDLEGSRTSV EQCYESTLSK LILERFQPEL
     ADKIFDSEDG HELEWLAEFI SHKNSRHLVY SLVEKHPDST LLNYCMKLIS EEGFQNEISH
     LNITTQRREL FSSVLLSAID AVLKEHRRGP MTDAYEKAFE KLVKVVCHGE HTYLYTQALL
     HVMSVERELF SSVLLSAIDA VLKEHRRGPM TDAYEKAFEK LVKVVCHGEH TYLYTQALLH
     VMSVEEQGME AAACAHISQS LRAVIQERGQ DPSQLYIALL QSNGEHIAPD AIQAMHIMVD
     KKCLNPADIS VLYREYTSPN PPPVELIRDP YFLDMLIDSL FAYDGVKVHK EYLSMYIYLL
     AYATCVGEKK NNGVRTQNRR DLDPTRDVIE ELLTLLRSKV DLAKEVKRLL NSIEVPVVAA
     GMLHYLRGVL LSKDMIGRPQ VVHLVLLDQI ATSHPNLQMR VFGIICDLYD RHTSSQDLTE
     EVMERQRVVI DRFVHLLSVG LVLPVVEKMS RMYRDGYIDS SLMRYFAIEV LQIVCPPYSQ
     DFTEVFLPIV SNKEIFIPTI HDKFELAKEF VDHCAQQLNS STTSLTSH
//